Product | EFEMP1 Antibody |
Description | Affinity Purified EGF-containing fibulin-like extracellular matrix protein 1 Antibody |
Verified Applications | ELISA, IHC, IP,WB |
Host | Rabbit |
Species Cross Reactivity | Human, Monkey, Mouse, Rat |
Immunogen | Synthetic cyclic peptide corresponding to N terminal amino acids 25-42 of Human EFEMP1, peptide was covalently modified. Sequence: TYTQCTDGYEWDPVRQQC |
Accession # | NCBI: XP_005264262.1 |
Physical Properties | |
Quantity | 100 µg |
Volume | 200 µl |
Concentration | 0.65 µg/µl in antibody stabilization buffer |
Form | Affinity Purified |
Clonality | Polyclonal |
Storage | -20⁰C for long term storage |
Application Protocol | |
DB | 1:10,000 |
ELISA | 1:10,000 |
| Immunohistochemistry | 1:100 |
Immunoprecipitation | 1:200 |
Western Blot | 1:500. Predicted molecular weight 60 kDa |
Protein | |
Uniprot # | UPI000387D485 |
Overview | Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth. |
Molecular Function | Calcium |
Subcellular Location | Secreted; Extracellular space |
Expression | In the eye, associated with photoreceptor outer and inner segment regions, the nerve fiber layer, outer nuclear layer and inner and outer plexiform layers of the retina. |
Structure | Interacts with ECM1. Interacts with TIMP3. |
Alternative Nomenclature | DHRD antibody Doyne honeycomb retinal degeneration antibody DRAD antibody EFEMP 1 antibody Epidermal growth factor containing fibulin like extracellular matrix protein 1 antibody FBLN3 antibody Fibrillin like antibody FIBULIN 3 antibody FLJ35535 antibody Heat shock 70 KD protein 1 antibody MGC111353 antibody MLVT antibody T16 protein antibody |
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