Product | Cyclin D1 Antibody Affinity Purified |
Description | Affinity Purified G1/S-specific cyclin-D1 Antibody C-epitope |
Verified Applications | ELISA, WB |
Host | Rabbit |
Species Cross Reactivity | Human |
Immunogen | Synthetic peptide corresponding to amino acid sequences 280-295 on human Cyclin D1 protein. |
Accession # | GenBank: AAH23620.1 |
Physical Properties | |
Quantity | 100 µg |
Volume | 200 µl |
Concentration | 0.65-0.70 µg/µl in antibody stabilization buffer |
Form | Affinity Purified |
Clonality | Polyclonal |
Determinant | C-epitope |
Storage | -20⁰C for long term storage |
Application Protocol | |
DB | 1:10,000 |
ELISA | 1:10,000 |
Western Blot | 1:500 |
Protein | |
Uniprot # | P24385 |
Overview | Regulatory component of the cyclin D1-CDK4 complex that phosphorylates and inhibits members of retinoblastoma protein family including RB1 and regulates the cell-cycle during G1/S transition. |
Molecular Function | Cell cycle; Cell division; DNA damage; Transcription regulation |
Subcellular Location | Cytoplasm; Membrane; Nucleus |
Structure | Belongs to the Cyclin D subfamily. Contains 1 cyclin N-terminal domain |
Alternative Nomenclature | B cell CLL/lymphoma 1 antibody CCND 1 antibody Cyl 1 antibody G1/S specific cyclin D1 antibody Parathyroid adenomatosis 1 antibody PRAD1 antibody U21B31 antibody |
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