General Information

Product

NKG2D Antibody Affinity Purified

Description

Affinity Purified NKG2-D type II integral membrane protein Antibody

Verified Applications

ELISA, WB

Host

Rabbit

Species Cross Reactivity

Bovine, Human, Monkey, Panda

Immunogen

Synthetic peptide taken within amino acid region 180-230 on rat NKG2D protein.

Accession #

NCBI: NP_598196.1

Physical Properties

Quantity

100 µg

Volume

200 µl

Concentration

0.55 µg/µl in antibody stabilization buffer

Form

Affinity Purified

Clonality

Polyclonal

Storage

-20⁰C for long term storage

Application Protocol

DB

1:10,000

ELISA

1:10,000

Western Blot

1:500

Protein

Uniprot #

O70215

Overview

Function as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells

Molecular Function

MHC class Ib receptor activity

Subcellular Location

Cell membrane, Membrane

Expression

Expressed by natural killer cells and by resting thoracic duct CD4+ and CD8+ T-cells, but not by thymocytes or other hemopoietic cells. Expressed by DC cells

Alternative Nomenclature

CD314 antibody

D12S2489E antibody

Killer cell lectin like receptor subfamily K member 1 antibody

KLR antibody

NK cell receptor D antibody

NK lectin-like receptor antibody

NKG2 D activating NK receptor antibody

NKLLR antibody

NKR P2 antibody