Product | EpCAM Antibody |
Description | Affinity Purified Tumor-associated Calcium signal transducer 1Antibody C-epitope |
Verified Applications | ELISA, IP, WB |
Host | Rabbit |
Species Cross Reactivity | Human |
Immunogen | Synthetic peptide taken within amino acid region 215-265on human Tumor-associated calcium signal transducer 1 protein. |
Accession # | GenBank: EAX00219.1 |
Physical Properties | |
Quantity | 100 µg |
Volume | 200 µl |
Concentration | 0.55-0.78 µg/µl in antibody stabilization buffer |
Form | Affinity Purified |
Clonality | Polyclonal |
Determinant | C-epitope |
Storage | -20⁰C for long term storage |
Application Protocol | |
DOT Blot | 1:10,000 |
ELISA | 1:10,000 |
| Immunoprecipitation | 1:200 |
Western Blot | 1:500 |
Protein | |
Uniprot # | UPI0000EE24A7 |
Overview | May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E. |
Molecular Function | Tumor antigen |
Subcellular Location | Cell junction, Cell membrane, Membrane, Tight junction |
Expression | Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESCs differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma. |
Structure | Belongs to EPCAM family. Contains 1 thryoglobulin type-1 domain. |
Alternative Nomenclature | 17 1A antibody 323/A3 antibody Adenocarcinoma associated antigen antibody Antigen identified by monoclonal antibody AUA1 antibody CD326 antibody Cell surface glycoprotein Trop 1 antibody Cell surface glycoprotein Trop 2 antibody CO17 1A antibody DIAR5 antibody EGP antibody EGP2 antibody EGP314 antibody EGP40 antibody Ep CAM antibody Epithelial cell adhesion molecule antibody Epithelial glycoprotein 314 antibody ESA antibody GA733 1 antibody gastrointestinal tumor-associated antigen 2, 35-KD glycoprotein antibody HNPCC8 antibody Human epithelial glycoprotein 2 antibody KS 1/4 antigen antibody KSA antibody Lymphocyte antigen 74 antibody M1S 1 antibody M1S2 antibody M4S1 antibody Major gastrointestinal tumor associated protein GA733 2 antibody Membrane component chromosome 4 surface marker (35kD glycoprotein) antibody MIC18 antibody MK 1 antibody TACD1 antibody TROP1 antibody Tumor associated calcium signal transducer 1 antibody Tumor associated calcium signal transducer 2 precursor antibody |
Protein information supplied by UniProt
>>> 更多资讯详情请访问蚂蚁淘商城
