General Information | |
Product | Phospho-RBM4 Antibody |
Description | Affinity Purified RNA binding motif protein 4 Antibody |
Verified Applications | ELISA, IP, WB |
Host | Rabbit |
Species Cross Reactivity | Human, Mouse, Rat |
Immunogen | Phosphorylated synthetic peptide taken within amino acid region 300-350 on human RNA binding motif protein 4. |
Accession # | GenBank: AAH32735 |
Physical Properties | |
Quantity | 100 µg |
Volume | 200 µl |
Concentration | 0.5-1.5 µg/µl in antibody stabilization buffer |
Immunoglobulin | IgG |
Form | Affinity Purified |
Purification Method | Immobilized antigen affinity chromatography |
Clonality | Polyclonal |
Storage | -20⁰C for long term storage |
Application Protocol |
ELISA | 1:50,000 |
Immunoprecipitation | 1:200 |
Western Blot | 1:2,500-1:5,000 |
Protein |
Uniprot # | Q9BWF3 |
Overview | RNA-binding factor involved in multiple aspects of cellular processes like alternative splicing of pre-mRNA and translation regulation. Modulates alternative 5"-splice site and exon selection. Acts as a muscle cell differentiation-promoting factor. Activates exon skipping of the PTB pre-mRNA during muscle cell differentiation. Antagonizes the activity of the splicing factor PTBP1 to modulate muscle cell-specific exon selection of alpha tropomyosin. |
Molecular Function | cyclin binding miRNA binding mRNA 3"-UTR binding mRNA binding pre-mRNA intronic binding pre-mRNA intronic pyrimidine-rich binding RNA binding zinc ion binding |
Subcellular Location | Nucleus, Cytoplasm |
Structure | Repeat, Zinc-finger |
Alternative Nomenclature | dkfzp547k0918 antibody hLark antibody lark antibody Lark homolog antibody mgc75138 antibody RBM4 antibody rbm4 lark antibody RNA binding motif 4 antibody RNA-binding motif protein 4a antibody RNA-binding protein 4 antibody |
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