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ChromoTekGmbH开创了一类新的免疫学研究工具，该工具源自细胞生物学和蛋白质组学的单域骆驼抗体。ChromoTek成立于2008年，由UlrichRothbauer周边的一个研究团队从慕尼黑路德维希马克西米利安大学（LMU）分拆而来，现已迅速发展成为著名的创新试剂供应商和大型制药公司值得信赖的服务提供商。我们的管理团队结合了互补的技能和经验，形成了持续增长的基础。

ChromoTek

ChromoTekGmbHpioneersanewclassofimmunologicresearchtoolsderivedfromsingledomaincamelantibodiesforcellbiologyandproteomics.Foundedin2008asaspin-offfromtheLudwig-MaximiliansUniversityMunich(LMU)byaresearchteamaroundUlrichRothbauer,ChromoTekhasrapidlydevelopedtobecomearenownedsupplierofinnovativereagentsaswellasatrustedserviceproviderforbigpharma.Ourmanagementteamcombinescomplementaryskillsandexperiencesthatformabasisforsustainedgrowth.

ChromoTekNano-Boosters是利用ATTO公司超高品质荧光素共价结合到小片段高特异性的GFP、RFP结合蛋白上，对变性荧光蛋白再激活，从而增强荧光信号，并增加荧光蛋白信号的稳定性。

  1.产品类型

  GFP-BoosterGFP融合蛋白免疫荧光增强剂

  RFP-BoosterRFP融合蛋白免疫荧光增强剂

  Vimentin-Booster波形蛋白丝免疫荧光增强剂(波形蛋白特异性羊驼抗体结构域)

  2.产品应用

  实验方法：免疫荧光(IF),免疫组化(IHC);

  实验对象：细胞系，组织切片;

  实验器材：荧光显微镜，激光共聚焦显微镜，超分辨率显微镜(3D-SIM，PALM,STED,STORM)

  3.产品优点

  图像分辨率更高

  在免疫荧光和超分辨显微镜中表现优异

  再激活变性荧光蛋白，增强荧光信号及荧光稳定性

  分子小，适用于超分辨率显微镜最小荧光位移标记

  德国ChromoTek公司成立于2008年，致力于细胞生物学和蛋白质组学的研发与研究。产品包括单克隆抗体、重组单域抗体、荧光抗体、GFP或RFP连接蛋白等。蚂蚁淘生物科技有限公司是德国ChromoTek公司的中国合作伙伴和签约总代理商

德国ChromoTek是一家专业研发生产标签抗体的公司，利用羊驼抗体的特异性解决了传统GFP/RFP抗体分子量过大、转染表达效率低的问题，研发出分子量只有15kDa的高特异性GFP抗体。ChromoTek公司的Nano-Traps是来自于alpaca羊驼的偶联有单价矩阵基质（琼脂糖珠，磁珠以及多孔板基质）的单结构域的抗体片段(VHHS)。主要的产品有GFP-Trap/RFP-Trap:emoji:。ChromoTek的产品分类一、Nano-Trap系列：以产品结合物为标准，包含磁珠系列和琼脂糖珠子系列，还有96板系列；抗体结合物包括GFPTrap，RFPTrap，GSTTrap，Dnmt1-Trap；Mk2-Trap；P53-Trap；Mdm4/HdmX-Trap二、Booster系列：含GFPboosterRFPbooster；三、可用于HCA实验的Chromobodies(质粒或细胞系形式)；四、高品质抗体（标签蛋白抗体和普通抗体）；ChromotekGFP-Traps已被600多篇同行评议的近期文献引用。

ChromoTekGmbHpioneersanewclassofimmunologicresearchtoolsderivedfromsingledomaincamelantibodiesforcellbiologyandproteomics.Foundedin2008asaspin-offfromtheLudwig-MaximiliansUniversityMunich(LMU)byaresearchteamaroundUlrichRothbauer,ChromoTekhasrapidlydevelopedtobecomearenownedsupplierofinnovativereagentsaswellasatrustedserviceproviderforbigpharma.Ourmanagementteamcombinescomplementaryskillsandexperiencesthatformabasisforsustainedgrowth.Ourmissionistodevelopandcommercializebettertoolsforourcustomersresearcharoundtheworld.Withaseriesofproductsandservicesunderdevelopment,ourvisionistobecomethemostrecognizedleaderinthefieldsofproteomicsandlivecellimaging.

Newtoolsforbetterresearch

  ChromoTek\'sproductscenteraroundtheproprietaryChromobody®technology.Forthat,theinnovativesingledomaincamelantibodyfragmentsareeithercoupledtoamatrix(Nano-Traps),toafluorescentdye(Booster)orfusedtoafluorescentprotein(Chromobodies®)orarepartofanassaysystemtostudyprotein-proteininteractions(F2H-Assay).Theirextremelysmallsizeandhighstabilitymakethemidealreagentsforbiomolecularresearchandlivecellassays.

  Nano-Traps(e.g.GFP-Trap®,RFP-Trap®),areroutinelyusedinthousandsoflabsallovertheworldtopulldowntaggedproteinsandinteractionpartnersthereoffromcellextracts,membraneornuclearpreparations.Theserecombinantbindingproteinsallowfast,efficientandreliableanalyticalandpreparativeone-steppurificationofproteinsforamultitudeofdownstreamapplications(WesternBlot,ChIP,Massspecetc.).

  Boosterareusefultoincreasethefluorescencesignalinvariousmicroscopyapplicationsbyattachingastablechemicalfluorescentdyetogreenfluorescentorredfluorescentproteintags.Theiradvantageistodeliverenhancedsensitivity,especiallyincaseswherephotobleachingofsamplesisaproblem.

  Ingeneticfusionwithafluorescentprotein,Chromobodies®arefunctionalinlivingcellswheretheydetectandvisualizeendogenoustargetstructuresinrealtime.WeleveragethisuniquefeatureofChromobodies®tobringhighcontent,dynamiclivecellimagingtoanextlevelofperformanceformediumtohighthroughputapplications(i.e.drugscreening).

  InadditiontoChromobody®basedbiosensortechnology,wehavedevelopedanewF2H-Assaytodirectlyvisualizeprotein-proteininteractionsinlivecells.Bytetheringafluorescentbaitatadefinedcellularstructurewegenerateapositionalprotein-proteininteractionbiosensorandassayforco-localizationoffluorescentpreyproteinsinlivingcells.Automatedimageacquisitionandanalysesallowustoperformhighthroughputscreensformoleculesanddrugsperturbingspecificprotein-proteininteractionsinthecellularenvironmentandinrealtime.

  Toroundupourproductportfolio,weofferadedicatedselectionofhighqualitymonoclonalantibodies.

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