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TG89

Chemical

C26H34N6O3S

510.7

936091-56-4

≥95%

Solid.

Soluble in DMSO or ethanol.

Manufactured by SynKinase.

Target: JAK2 | Kinase Group: PTK | Substrate: TyrosineClick here for Original Manufacturer Product DatasheetOur product description may differ slightly from the original manufacturers product datasheet.

OOSKXASFJFSOBK-UHFFFAOYSA-N

AMBIENT

+4°C

-20°C

Stable for at least 2 years after receipt when stored at -20°C.

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TG-89 is a JAK inhibitor. It has IC(50) values of 6, 25, 17 and 169nM against JAK2, FLT3, RET and JAK3 respectively.Product References

TG101209, a small molecule JAK2-selective kinase inhibitor potently inhibits myeloproliferative disorder-associated JAK2V617F and MPLW515L/K mutations: A. Pardanani, et al.; Leukemia 21, 1658 (2007)

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