More Information Product Details Synonyms Product Type Properties Formula MW CAS Purity Chemicals Appearance Solubility Declaration Other Product Data InChi Key Shipping and Handling Shipping Short Term Storage Long Term Storage Use/Stability Documents MSDS Product Specification Sheet Datasheet

AC-480; BMS599626

Chemical

C27H27FN8O3

530.6

714971-09-2

≥95%

Solid.

Soluble in DMSO or ethanol.

Manufactured by SynKinase.

Target: EGFR - HER2 | Kinase Group: RTK | Substrate: TyrosineClick here for Original Manufacturer Product DatasheetOur product description may differ slightly from the original manufacturers product datasheet.

LUJZZYWHBDHDQX-QFIPXVFZSA-N

AMBIENT

+4°C

-20°C

Stable for at least 2 years after receipt when stored at -20°C.

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BMS-599626 is an orally bioavailable, highly selective and potent pan-HER kinase inhibitor. It inhibits HER1 and HER2 with IC(50) values of 20 and 30nM, respectively.Product References

Preclinical antitumor activity of BMS-599626, a pan-HER kinase inhibitor that inhibits HER1/HER2 homodimer and heterodimer signaling: T.W. Wong, et al.; Clin. Cancer Res. 12, 6186 (2006)

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