More Information Product Details Synonyms Product Type Properties Source/Host Sequence Crossreactivity Specificity Biological Activity MW Purity Endotoxin Content Concentration Reconstitution Formulation Other Product Data Shipping and Handling Shipping Short Term Storage Long Term Storage Handling Advice Use/Stability Documents MSDS Product Specification Sheet Datasheet

B Cell Maturation Protein; CD269; TNFRSF17

Protein

HEK 293 cells

The extracellular domain of mouse BCMA (aa 1-46) is fused at the C-terminus to the Fc portion of human IgG1.

HumanMouse

Binds mouse and human BAFF and APRIL.

Blocks the binding of mouse BAFF and human APRIL to their receptors BCMA and TACI.

~35kDa (SDS-PAGE)

≥95% (SDS-PAGE)

1mg/ml after reconstitution.

Reconstitute with 50μl sterile water.

Lyophilized. Contains PBS.

UniProt link O88472: BCMA (mouse)

BLUE ICE

+4°C

-20°C

After reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.PBS containing at least 0.1% BSA should be used for further dilutions.

Stable for at least 6 months after receipt when stored at -20°C.

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BCMA is a receptor for BAFF and APRIL. It promotes B cell survival and plays a role in the regulation of humoral immunity. Its downstream signaling is dependent on NF-κB and JNK.

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