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Zyvox

Chemical

C16H20FN3O4

337.4

165800-03-3

≥95%

Solid.

Soluble in DMSO or ethanol.

Manufactured by SynKinase.

Target: Ribosome (23S) | Kinase Group: N/A | Substrate: N/AClick here for Original Manufacturer Product DatasheetOur product description may differ slightly from the original manufacturers product datasheet.

TYZROVQLWOKYKF-ZDUSSCGKSA-N

AMBIENT

+4°C

-20°C

Stable for at least 2 years after receipt when stored at -20°C.

No

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Linezolid displays potent antibacterial activity against a variety of multidrug-resistant gram-positive microbes in vitro and in vivo, including streptococcus and methicillin-resistant Staphylococcus aureus (MRSA). Linezolid has shown excellent efficacy against gram-positive cocci, including Staphylococcus aureus, coagulase-negative staphylococci, enterococci, and streptococci, with MICs ranging from 0.5 to 4µg/ml. Linezolid is a potent inhibitor of cell-free transcription-translation in E. coli, exhibiting 50% inhibitory concentrations (IC50s) of 1.8µM. The drug works by inhibiting the initiation of bacterial protein synthesis and has excellent bioavailability in animal studies.Product References

Vancomycin versus linezolid in the treatment of methicillin-resistant Staphylococcus aureus meningitis: O.R. Sipahi, et al.; Surg. Infect. (Larchmt) 14, 357 (2013)

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