HPV(Type16&18,E6)HumanPapillomaVirusEarlyProtein6Cataloguenumber:HP305

Clone	C1P5
Isotype	IgG1
ProductType	MonoclonalAntibodyPrimaryAntibodies
Units	3ml
Host	Mouse
Application	Immunohistochemistry(frozen&paraffin)Immunohistochemistry(frozen)Immunohistochemistry(paraffin)

BackgroundThisantibodyisusedforthedetectionofhighriskHumanPapillomavirus(HPV)infectionsindifferenttissues.ItshouldalwaysbeusedwhenthescreeningantibodyhasdetectedthepresenceofpapillomavirusinsUSPectedtissues.HumanPapillomavirustype16and18areresponsIBLeforthedevelopmentofcervicalcarcinoma,aswellascarcinomasoftheheadandneckregionandsomeothertumors.

SourceMouseimmunizedwithrecombinantE6proteinfroHPV18

Immunogen:HPVtype18E6proteinproducedinbacteria

ProductAntibodysolutioninstABIlizingphosphatebufferpH7.3.Contains0.09%sodiumazide**.Thevolumeissufficientforatleast30immunohistochemicaltests(100µlworkingsolution/test).Useappropriateantibodydiluente.g.BIOLOGOArt.No.PU002ifrequired.

PurificationMethod:AntibodysolutioninstabilizingphosphatebufferpH7.3.Contains0.09%sodiumazide**.Thevolumeissufficientforatleast30immunohistochemicaltests(100µlworkingsolution/test).Useappropriateantibodydiluente.g.BIOLOGOArt.No.PU002ifrequired.

SecondaryReagents:WerecommendtheuseofBIOLOGO"sUniversalStainingSystemDAB(Art.No.DA005)orAEC(Art.-No.AE005).

SpecificityHumanPapillomavirusEarlyAntigenE6fromHPV16and18.

ApplicationsIHC(C,P)

IncubationTime:60minatRT

WorkingConcentration:(RTU)neat

Pre-Treatment:ImprovementofstainingwithunmaskingfluidG(Art.No.DE007)orunmaskingfluidC(Art.No.DE000)

PositiveControl:HPV-positivevulvacarcinoma

Storage2-8°C

CautionThisproductisintendedFORRESEARCHUSEONLY,andFORTESTSINVITRO,notforuseindiagnosticortherapeuticproceduresinvolvinghumansoranimals.Itmaycontainhazardousingredients. PleaserefertotheSafetyDataSheets(SDS)foradditionalinformationandproperhandlingprocedures.Disposeproductremaindersaccordingtolocalregulations.Thisdatasheetisasaccurateasreasonablyachievable,butNordic-Mubio​acceptsnoliabilityforanyinaccuraciesoromissionsinthisinformation.

References1.Cowsertetal.(1987)J.Natl.CancerInst.79;1053-1057.2.BanksL.J.(1987)J.Gen.Virol.68;1351-1355.3.CasonJ.,PatelD.,NaylorJ.,etal.(1989)Identificationofimmunogenicregionsofthemajorcoatproteinofhumanpapillomavirustype16thatcontaintype-restrictedepitopes.J.GeneralVirol.70;2973-2987.4.ShepherdP.S.,LunnyD.,BrooksR.,etal.(1992)Thedetectionofhumanpapillomavirusesincervicalbiopsiesbyimmunohistochemistryandinsituhybridization.Scand.J.Immunol.36(11);69-74.

SafetyDatasheet(s)forthisproduct:NM_SodiumAzide/wp-content/uploads/SDS/AntibodySDSwithSodiumAzideNoridic-MUbio.pdf

Nordic的纯化的牛IgG可以在各种免疫测定（包括免疫扩散，免疫电泳，ELISA，Western印迹，斑点免疫结合测定（DIBA），血细胞凝集和细胞结合测定）中用作参考抗原，校准物，包被蛋白和封闭剂。该产品仅用于研究目的，并且用于体外测试，不适用于涉及人或动物的诊断或治疗程序。它可能包含有害成分。请参阅安全数据表（SDS）了解更多信息和正确的处理程序。根据当地法规处理产品残留物。此数据表的准确性尽可能合理，但Nordic-MUbio对本信息中的任何准确性或遗漏概不负责。