Species:MouseImmunogen:TAG-72 protein (B72.3 & CC49)Clone:B72.3 & CC49Isotype:IgG1, kappa (B72.3 & CC49)Species Reactivity:Human, Cow, Dog, and Rat. Others not known.Positive Control:Jurkat cells, breast or lung carcinoma.Specificity:Recognizes an oncofetal antigen of 220kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This antibody defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80% sensitivity and 93% specificity for pulmonary adenocarcinoma. Therefore, TAG-72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur, so results must be interpreted with the utmost degree of caution.Status:RUO PolyTek，抗兔聚合HRP已开发，具有成本效益，可提供最清洁，最一致的染色。该系统基于聚合的过氧化物酶标记，该标记从等式中消除了生物素，从而消除了背景染色的主要原因。