Species:MouseClone:Pab1801 & DO-7Isotype:IgG1 & IgG2b, KappaMW:53 kDSpecies Reactivity:HumanPositive Control:About 50% of breast carcinomas are positive for p53, especially those lacking estrogen and/or progesterone receptor, or with high proliferation index.Specificity:This antibody reacts with wild as well as mutant types of p53 protein.It recognizes an epitope in the N-terminus of p53 protein.p53 is a 53 kD phosphoprotein known as tumor suppressor gene product.About 50% of breast carcinomas are positive for p53 especially those lacking estrogen and/or progesterone receptors.This antibody can be demonstrated in 22-76% of colon, stomach, bladder, breast, lung and testes cancers. Its epitope maps within the N-terminus (aa 32-79) of p53. PolyTek，抗兔聚合HRP已开发，具有成本效益，可提供最清洁，最一致的染色。该系统基于聚合的过氧化物酶标记，该标记从等式中消除了生物素，从而消除了背景染色的主要原因。