Background
Lung cancer is a heterogeneous disease, which can be subdivided into five major tyoes based on histopathological criteria like squamous cell carcinomas, adenocarcinoma, large cell carcinoma, adenosquamous carcinoma and small cell lung cancer (SCLC). A number of important prognostic characteristics have been identified to include the extend of disease and especially for SCLC, tumor sensitivity to chemotherapy. The monoclonal antibody MOC-1 is reactive with lung cancer associated antigens and stains neural and a variable number of endocrine tissues. In the lung it reacts preferentially with SCLC and carcinoids. MOC-1 was defined as a cluster I antibody during the First International Workshop on Small Cell Lung Cancer (SCLC) Antibodies. MOC-1 recognizes NCAM which is present in small cell lung cancer (SCLC) and lung carcinoids.
Species Reactivity
Human,Mouse
Product Usage
MOC-1 is reactive with almost all SCLC cases and has a molecular weight of about 145 kD.
Product Type
Primary Antibodies
Applications
Flow Cytometry,Immunocytochemistry,Immunohistochemistry (frozen),Western blotting
Fields of Interest
Cancer,Cell adhesion, CD Markers
Product Source
MOC-1 is a Mouse monoclonal IgG1 antibody and is coming from a small cell lung carcinoma derived cell line preparation. Hybridoma's: Mouse myeloma X 63-BALB/c.
Product Formulation
Each vial contains 1ml of culture supernatant of monoclonal antibody containing 0.09% sodium azide.
Storage Conditions
Store at 4
Exalpha血清是凝结后残留的全血液体部分。通过离心将该液体部分与凝结的细胞和凝血因子分离。它包含蛋白质的混合物,包括抗体(免疫球蛋白),血清白蛋白,α和β球蛋白以及调节蛋白,例如激素和酶。我们从人类,灵长类和兽医物种中提取的血清和牛奶可用于多种用途;研究血清或牛奶的正常蛋白质组成,作为参考蛋白质,阻断剂或阴性对照。