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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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商品描述
ProductCode
ProductName
GoatantiHumanplasminogen
Size
1ml
Price(USD)
$204
Background
Thedefinedantibodyreactivityisrestrictedtoplasminogenastestedatthelevelofsensitivityofimmuno-precipitationtechniques.Asingleprecipitinlineisobtainedinbidimensionalelectrophoresis,immunoelectrophoresisanddoublerADIalimmunodiffusion(Ouchterlony)whichshowsareactionoffullidentitywiththepurifiedimmunogen.Noprecipitationisobtainedwithanyotherplasmaproteinorwithplasminogen-deficientplasma.Theantiserummayalsoreactwithplasminconversionintermediatesandwithplasmin.Inprecipitatingtechniquesaselectroimmunodiffusion(Laurell),immunoelectrophoresis,singleanddoubleradialimmunodiffusion(Mancini,Ouchterlony),immunonephelometry,solidphaseassays;ascatchingordetectionantibodyinELISA.EDTAshouldbeaddedtotheplasmasamplesandallassaycomponentstostABIlizetheproteins;topreventactivationofplasminogeninplasmasamplesepsilonaminocaproicacidmaybeadded.
Host
Goat
SpeciesReactivity
Human
ProductUsage
PrecipitatingpolyclonalGoatantiSerumtoHumanplasminogen
ProductType
PrimaryAntibodies
Applications
Immunoprecipitation
FieldsofInterest
Cardiovascular
ProductSource
Nativeplasminogenisasinglepolypeptidechain,synthesizedintheliver.Itsmolecularweighthasbeenreportedtobe81,000and92,000.Partofthemoleculecontainstheactiveserineesteraseofplasmin.Onactivationitisconvertedtotwopolypeptidechainslinkedbydisulphidebridges.Threedifferentabnormalmolecularformsofplasminogenhavebeendescribed.Normaladultplasmacontains10-20mg/100mlplasminogen.Differentcongenitalmolecularstructureabnormalitiesassociatedwithrecurrentthrombosishavebeendescribed,butareextremelyrare.Inliverdiseaseplasminogenactivitymaybereduced.Freund
ProductFormulation
Delipidated,heatinactivated,lyophilized,stablewholeserum.Nopreservativeadded.TotalproteinandIgGconcentrationsintheantiserumarecomparabletothoseofpoolednormalgoatserum.Noforeignproteinsadded.
ProductSpecificity
TheantiSerumdoesnotcross-reactwithanyotherHumanplasmaproteinsastestedingel-diffusiontechniques.Inter-speciescross-reactivityisanormalfeatureofantibodiestoplasmaproteins,sincehomologousproteinsofdifferentspeciesfrequentlyshareantigenicdeterminants.Cross-reactivityofthisantiSerumhasnotbeentestedindetail,howeverindoubleradialimmunodiffusioneareactionhasbeenobservedwithBovine,DogandrhesusMonkey.
StorageConditions
Thelyophilizedantiserumisshippedatambienttemperatureandmaybestoredat+4
