Kim-1 is a type I trans-membrane structural glycoprotein located in the renal proximal tubule epithelial cells.  These cells undergo regeneration after various forms of injury and shed Kim-1 antigen into the urine.  Thus, urinary Kim-1 is an early and specific biomarker for tubular kidney injury.  Kim-1 has become widely recognized by many organizations and agencies, including the FDA, as an excellent biomarker in pre-clinical studies to monitor acute kidney tubular toxicity by identifying adverse reactive drugs and therapeutic agents in drug development.

Kidney injury caused by therapeutic agents and drug induction is a common type of injury requiring appropriate monitoring and intervention.  Current standards using blood urea nitrogen and creatinine are considered late indicators of kidney injury and are often non-specific.  Kim-1 has been shown continually to outperform traditional biomarkers of kidney injury in preclinical biomarker studies. The detection of Kim-1 can occur in as little as six hours post injection of an agent known to cause kidney injury.

The Rat Rena-strip test is a 15-minute qualitative (or quantitative with optional reader) lateral flow assay. Rat urine samples are added to the cassette and results can be read within 15 minutes.

Specifications:

Kit Contents:

• Rat Rena-strip cassettes in white foil pouches with dessicant, 25 cassettes

Storage Temperature: Store at room temperature.

Shipping Temperature: Ambient

Stability: 2 years from date of manufacture

Product is for research use only.

BioAssay Works裸金® 20纳米浓缩金溶胶$ 58.50 – $ 2,601.10可用选项评分：类别：金溶胶标签：胶体金，胶体金溶胶，金纳米颗粒，金溶胶在15 OD / mL下浓缩20 nm金溶胶。可用选项： 卷 任何1毫升 9毫升 44毫升 100毫升 SKU 描述 价钱 NG20-B10020 nm浓缩金溶胶，100 mL$ 2,601.10添加到购物车NG20-B04420 nm浓缩金溶胶，44 mL$ 1,357.00添加到购物车NG20-B00120 nm浓缩金溶胶，1 mL$ 58.50添加到购物车NG20-B00920 nm浓缩金溶胶，9 mL$ 351.10添加到购物车产品描述裸金®  20nm的浓缩金溶胶是金纳米颗粒的高度均匀的溶液。这些金溶胶可以与多种抗体或可溶性蛋白缀合。裸金溶胶是通过专有工艺生产的，该工艺不涉及传统的沸腾和离心方法。通过这种独特的过程，可以将抗体或可溶性蛋白包被在金纳米颗粒上，而无需通过离心浓缩金–从而节省了时间，并减少了蛋白质和所得缀合物的浪费。另外，消除了对浓缩金的需要，使结合过程中聚集体的形成最小化。裸金20 nm浓缩金溶胶有几种不同的体积（1 mL，9 mL，44 mL和100 mL），可满足您的特定需求。规格：OD / mL：15储存温度：室温，请勿冻结！运输温度：环境稳定性：自生产之日起2年