OVERVIEW:
| Monoclonal EBV antibody (gp250/350), Anti-EBV antibody (gp250/350), EBV gp250/350 antibody, Epstein Barr Virus antibody |
| EBV |
| This antibody recognizes the envelope glycoprotein complex 250/350 of EBV |
| IF |
| EBV antibody (gp250/350) was raised in mouse using envelope glycoprotein complex 250/350 as the immunogen. |
SPECIFICATIONS:
| Mouse |
| M5042522 |
| IgG1 |
| > 90% pure |
| Liquid in 10 mM PBS, pH 7.2, with 0.1% NaN3. |
| Batch dependent |
STORAGE & SAFETY:
| Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles |
| This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product. |
Usage Assay Information:
| Optimal conditions to be determined by end user |
GENERAL INFORMATION:
| The Epstein-Barr virus (EBV), also called human herpesvirus 4 (HHV-4), is a virus of the herpes family, which includes herpes simplex virus 1 and 2, and is one of the most common viruses in humans. It is best known as the cause of infectious mononucleosis. It is also associated with particular forms of cancer, particularly Hodgkins lymphoma, Burkitts lymphoma, nasopharyngeal carcinoma, and central nervous system lymphomas associated with HIV. To infect B cells, the gp350 viral protein binds to the cellular receptor complement receptor 2 (CR2), and triggers endocytosis. To infect epithelial cells, gp350 also binds to CR2; however, endocytosis is not triggered. |
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