OVERVIEW:
| Monoclonal Axin1 antibody, Anti-Axin1 antibody, AXIN antibody, Axin -1, Axis inhibition protein 1 antibody, Axin 1, Axin1, hAxin antibody, Axin -1 antibody, Axin 1 antibody, Axin-1 antibody, axin 1 antibody, MGC52315 antibody |
| Human |
| To be determined by end-user. |
| ELISA, IF, WB |
| Axin1 antibody was raised in mouse using recombinant human Axin1 (546-752aa) purified from E. coli as the immunogen. |
SPECIFICATIONS:
| Mouse |
| AT1A4 |
| IgG2b kappa |
| Anti-human Axin1 antibody, clone AT1A4, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Axin1 protein. |
| Axin1 antibody was purified by protein-G affinity chromatography |
| Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3. |
| 1 mg/ml |
STORAGE & SAFETY:
| Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
Usage Assay Information:
| IF: 1:250-:500, WB: 1:250-1:500 |
GENERAL INFORMATION:
| Axin was originally identified as the product of the mouse gene called ?fused? or fu (renamed Axin), and has since been shown to play a crucial role in controlling axis formation during embryonic development. Axin1 is characterized to be a tumor suppressor and numerous gene mutations have been identified throughout Axin1 from a number of different cancers. Axin can identify in a mouse mutant strain, created by random integration of a transgene. Also, Axin1 plays an important role in the formation of the embryonic neural axis. Recently, it was reported that Axin is found in mitotic spindles and centrosomes. |
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