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4000-520-616 / 18915418616
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0512-67156496
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商品描述
OVERVIEW:
| Synonyms | MonoclonalAxin1antibody,Anti-Axin1antibody,AXINantibody,Axin-1,Axisinhibitionprotein1antibody,Axin1,Axin1,hAxinantibody,Axin-1antibody,Axin1antibody,Axin-1antibody,axin1antibody,MGC52315antibody |
|---|---|
| Specificity | Human |
| CrossReactivity | Tobedeterminedbyend-user. |
| Applications | ELISA,IF,WB |
| Immunogen | Axin1antibodywasraisedinmouseusingrecombinanthumanAxin1(546-752aa)purifiedfromE.coliastheimmunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | AT1A4 |
| Isotype | IgG2bkappa |
| Source | Anti-humanAxin1antibody,cloneAT1A4,isderivedfromhybridizationofmouseF0myelomacellswithspleencellsfromBALB/cmiceimmunizedwitharecombinanthumanAxin1protein. |
| MethodofPurification | Axin1antibodywaspurifiedbyprotein-Gaffinitychromatography |
| Form&Buffer | SuppliedasaliquidinPBS,pH7.4,with0.1%NaN3. |
| Concentration | 1mg/ml |
STORAGE&SAFETY:
| Storage | Storeat4degCforshorttermstorage.Aliquotandstoreat-20degCforlongtermstorage.Avoidrepeatedfreeze/thawcycles. |
|---|
UsageAssayInformation:
| UsageRecommendations | IF:1:250-:500,WB:1:250-1:500 |
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GENERALINFORMATION:
| BIOLOGicalSignificance | Axinwasoriginallyidentifiedastheproductofthemousegenecalled?fused?orfu(renamedAxin),andhassincebeenshowntoplayacrucialroleincontrollingaxisformationduringembryonicdevelopment.Axin1ischaracterizedtobeatumorsuppressorandnumerousgenemutationshavebeenidentifiedthroughoutAxin1fromanumberofdifferentcancers.Axincanidentifyinamousemutantstrain,createdbyrandomintegrationofatransgene.Also,Axin1playsanimportantroleintheformationoftheembryonicneuralaxis.Recently,itwasreportedthatAxinisfoundinmitoticspindlesandcentrosomes. |
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