Reaction Biology详细产品列表：

货号	产品	价格（美元）
HMT-11-376	ASH1L (His) Methyltransferase	325
DMT-21-124	DNMT1	450
DMT-21-125	DNMT3a Methyltransferase	450
DMT-21-126	DNMT3b	450
HMT-11-101	DOT1L Methyltransferase	395
HMT-25-115	EZH1 Complex	450
HMT-25-114	EZH2 Complex	799
HMT-25-173	EZH2-Y641F Complex	799
HMT-11-102	G9a Methyltransferase (GST) (aa 786-1210)	299
HMT-11-245	G9a Methyltransferase (His) (aa 913-1193)	299
HMT-12-104	G9a/GLP Complex Methyltransferase	325
HMT-11-103	GLP Methyltransferase Protein	299
HMT-15-105	MLL1 Complex	499
HMT-15-106	MLL2 Complex	499
HMT-15-107	MLL3 Complex	499
HMT-15-108	MLL4 Complex	499
MT-11-359	NNMT (GST) (Nicotinamide N-Methyltransferase)	299
MT-11-358	NNMT (His) (Nicotinamide N-Methyltransferase)	299
HMT-11-319	NRMT1 (GST)	325
HMT-21-139	NSD1 Methyltransferase	450
HMT-21-138 0	NSD2 (His) Methyltransferase	450
HMT-21-122	NSD2 Methyltransferase	550
HMT-11-377	NSD2 SET (His)	325
HMT-21-159	NSD2-E1099K Methyltransferase	599
HMT-11-378	NSD2-E1099K-SET (His)	325
HMT-21-181	NSD2-T1150A Methyltransferase	450
HMT-11-379	NSD2-T1150A-SET (His)	325
HMT-11-132	NSD3 Methyltransferase	325
HMT-21-348	PRDM2 Methyltransferase	325
HMT-21-152	PRDM9 Methyltransferase	450
HMT-11-119	PRMT1 Methyltransferase	325
HMT-11-113	PRMT3 Methyltransferase	325
HMT-11-120	PRMT4 Methyltransferase	399
HMT-21-172	PRMT5 Methyltransferase	450
HMT-22-434	PRMT5(C449S)/MEP50	799
HMT-22-148	PRMT5/MEP50 Complex	799
HMT-11-121	PRMT6 Methyltransferase (GST)	325
HMT-21-380	PRMT6 Methyltransferase (His)	325
HMT-21-382	PRMT7 (His)	450
HMT-11-135	PRMT8 Methyltransferase	325
MT-11-356	s-COMT (His) (Soluble Catechol-O-Methyltransferase)	299
MT-11-357	s-COMT (V108M) (His) (Soluble Catechol-O-Methyltransferase）	299
HMT-15-116	SET1A Complex (5-subunits)	499
HMT-15-117	SET1B Complex (5-subunits)	499
HMT-11-133	SET7/9 Methyltransferase	299
HMT-11-476	SET8 (GST)	299
HMT-11-118	SET8 Methyltransferase	299
HMT-11-128	SETD2 (GST) Methyltransferase	299
HMT-11-129	SETD2 (His) Methyltransferase	299
HMT-11-110	SMYD2 Methyltransferase	325
HMT-11-111	SUV39H1 Methyltransferase	299
HMT-11-418	SUV39H2 (GST) Methyltransferase	299
HMT-11-112	SUV39H2 (His) Methyltransferase	299
HMT-21-149	SUV420H1-tv1 Methyltransferase	450
HMT-21-150	SUV420H1-tv2 Methyltransferase	450
HMT-21-349	SUV420H2 Methyltransferase	325
HMT-14-109	WRAD2	375
HMT-14-438	(H3.3-H4)2 Tetramer	325
HMT-35-435	Core Histones (Chicken)	250
HMT-11-184	Fibrillarin (GST)	325
HMT-11-183	Fibrillarin (His)	325
HMT-11-137	GST-GAR	299
HMT-12-316	H2A/H2B dimers	325
HMT-11-180	Histone H1.0	50
HMT-11-146	Histone H2A	50
HMT-11-147	Histone H2B	50
HMT-11-134	Histone H3.3	50
HMT-35-179	Nucleosomes (Chicken Mono/Di)	280
HMT-35-182	Nucleosomes (Chicken Oligo/Poly H5 Enriched)	280

Reaction Biology描述：

人类重组EZH2incomplexwithhumanrecombinantsEED.TotalcomplexMWis228.7kDa.Allproteinsarefull长度（residue2throughC末端）也是全美-expressedinaninsectcell / baculovirusexpressionsystem.TheEEDsubunitincorporatesanN-terminalStrepandFlag-tagandallothersincludeanN-terminalHis-tag.CatalyzesthetransferofmethylgroupsfromS腺苷-L-甲硫氨酸（SAM）tothee-aminofunctionofproteinL-lysineresidues，specificallylysine-27ofhistoneH3（ H3K27）。在开发过程中，Polycomb Repressive Complex 2（PRC2）是主要的甲基转移酶对IBL的反应eforgeneratingtrimethylatedhistoneH3lysine-27（的H3K27me3），anepigeneticmarkessentialforprogrammedrepressionofgeneexpression1-5.EZH2，whichincludesaSETmethyltransferasedomain，isthecatalyticsubunitofPRC21,6.ThecoreofthecatalyticcomplexincludesEZH2，EED，SUZ12andRbAp48，whileadditionofAEBP2significantlyenhancesthemethyltransferaseactivityofthecomplex（> 3×）6.EZH2isoverexpressedinawiderangeofhumancancersanditsoverexpressioncancorrelatewithtumorprogression，increasedmetastasisandpoorprognosis（seereview7）.DepletionofEZH2and / orotherPRC2componentscaninhibitgrowthorinduceapoptosisincancercells6,8-10.Consequently，EZH2isconsideredapromisingtargetforthedevelopmentofanti -癌症疗法11

存取编号：EZH2NM_001203247，EEDNM_003797，SUZ12NM_015355

包括酰胺酸：EZH22-746，EED2-441，SUZ122-739

标记（S）：EEDhasanN末端链霉菌标记标签，其他所有N末端His标签

分子量：228.7kDa

EXPRESSIONSYSTEM：昆虫细胞/杆状病毒

SUPPLIEDAS：Solutionofpurifiedrecombinantproteinin20mMTris盐酸，pH8,150mMNaCl，2mMMgCl2，2mMDTT，20％甘油（w / v），0.01％NP-40asdeterminedbyOD280。

储存：-70°C。在使用前应迅速融化并储存。应保留未使用的未稀释蛋白质，例如干燥/冰乙醇液中的氮。尽可能减少冻融/解冻，但不建议使用稀释体积太小（<5µl）的稀释蛋白质。

Reaction Biology公司成立于2001年，是专门从事早期药物发现化验服务的公司，提供广泛的服务，包括用于激酶和表观遗传生物化学以及基于细胞的高通量筛选（HTS）和选择性化合物分析的稳定测定技术。我们还提供相关的HTS检测试剂，包括高度纯化和特征化的表观遗传蛋白。平均每年进行数百万次HTS和性能分析。在全球有超过750家公司（包括制药，生物技术，学术和非营利实验室）购买我们的产品。货号 产品 价格（美元）HMT-11-376 ASH1L (His) Methyltransferase 325DMT-21-124 DNMT1 450DMT-21-125 DNMT3a Methyltransferase 450DMT-21-126 DNMT3b 450HMT-11-101 DOT1L Methyltransferase 395HMT-25-115 EZH1 Complex 450HMT-25-114 EZH2 Complex 799HMT-25-173 EZH2-Y641F Complex 799HMT-11-102 G9a Methyltransferase (GST) (aa 786-1210) 299HMT-11-245 G9a Methyltransferase (His) (aa 913-1193) 299HMT-12-104 G9a/GLP Complex Methyltransferase 325HMT-11-103 GLP Methyltransferase Protein 299HMT-15-105 MLL1 Complex 499HMT-15-106 MLL2 Complex 499HMT-15-107 MLL3 Complex 499HMT-15-108 MLL4 Complex 499MT-11-359 NNMT (GST) (Nicotinamide N-Methyltransferase) 299MT-11-358 NNMT (His) (Nicotinamide N-Methyltransferase) 299HMT-11-319 NRMT1 (GST) 325HMT-21-139 NSD1 Methyltransferase 450HMT-21-138 0 NSD2 (His) Methyltransferase 450HMT-21-122 NSD2 Methyltransferase 550HMT-11-377 NSD2 SET (His) 325HMT-21-159 NSD2-E1099K Methyltransferase 599HMT-11-378 NSD2-E1099K-SET (His) 325HMT-21-181 NSD2-T1150A Methyltransferase 450HMT-11-379 NSD2-T1150A-SET (His) 325HMT-11-132 NSD3 Methyltransferase 325HMT-21-348 PRDM2 Methyltransferase 325HMT-21-152 PRDM9 Methyltransferase 450HMT-11-119 PRMT1 Methyltransferase 325HMT-11-113 PRMT3 Methyltransferase 325HMT-11-120 PRMT4 Methyltransferase 399HMT-21-172 PRMT5 Methyltransferase 450HMT-22-434 PRMT5(C449S)/MEP50 799HMT-22-148 PRMT5/MEP50 Complex 799HMT-11-121 PRMT6 Methyltransferase (GST) 325HMT-21-380 PRMT6 Methyltransferase (His) 325HMT-21-382 PRMT7 (His) 450HMT-11-135 PRMT8 Methyltransferase 325MT-11-356 s-COMT (His) (Soluble Catechol-O-Methyltransferase) 299MT-11-357 s-COMT (V108M) (His) (Soluble Catechol-O-Methyltransferase） 299HMT-15-116 SET1A Complex (5-subunits) 499HMT-15-117 SET1B Complex (5-subunits) 499HMT-11-133 SET7/9 Methyltransferase 299HMT-11-476 SET8 (GST) 299HMT-11-118 SET8 Methyltransferase 299HMT-11-128 SETD2 (GST) Methyltransferase 299HMT-11-129 SETD2 (His) Methyltransferase 299HMT-11-110 SMYD2 Methyltransferase 325HMT-11-111 SUV39H1 Methyltransferase 299HMT-11-418 SUV39H2 (GST) Methyltransferase 299HMT-11-112 SUV39H2 (His) Methyltransferase 299HMT-21-149 SUV420H1-tv1 Methyltransferase 450HMT-21-150 SUV420H1-tv2 Methyltransferase 450HMT-21-349 SUV420H2 Methyltransferase 325HMT-14-109 WRAD2 375HMT-14-438 (H3.3-H4)2 Tetramer 325HMT-35-435 Core Histones (Chicken) 250HMT-11-184 Fibrillarin (GST) 325HMT-11-183 Fibrillarin (His) 325HMT-11-137 GST-GAR 299HMT-12-316 H2A/H2B dimers 325HMT-11-180 Histone H1.0 50HMT-11-146 Histone H2A 50HMT-11-147 Histone H2B 50HMT-11-134 Histone H3.3 50HMT-35-179 Nucleosomes (Chicken Mono/Di) 280HMT-35-182 Nucleosomes (Chicken Oligo/Poly H5 Enriched) 280

蚂蚁淘(ebiomall)是苏州蚂蚁淘生物科技有限公司旗下的生物医学科研用品跨境直采（平行进口）平台，自营B2B电商。客户在蚂蚁淘搜索全球产品信息，找到合适的产品后再蚂蚁淘下单，然后蚂蚁淘的海外办事处进行跨境采购、运输到中国口岸，最后由蚂蚁淘国内团队清关并发货给客户

我们部分客户

1 : 经销商代表---国药化试，飞世尔，SIGMA等1000家左右的经销商

2 : 学校代表---北京大学，清华大学，上海交通大学，复旦大学，武汉大学，厦门大学.....等200所左右大学及100多家附属医院

3 : 制药公司代表 : 罗氏，阿斯利康，诺和诺德，和记黄埔，东阳光科......

4 : CRO公司代表 : 睿智化学，药明康德，桑迪亚，美迪西......

>>> 更多资讯详情请访问蚂蚁淘商城