IhavecomparedMabtechELISpotassaytoELISpotassayswerunatourcompanyonregularbasis"head-to-head"usingidenticalsamples.Mabtech"skitsprovedtobesuperiortoourprotocol,hadsignificantlylowerbackgroundandprovidedbetterandhigherdetectionofspots.
Mabtech提供了多种不同格式的ELISpot试剂盒,用于检测非人类灵长类动物(NHP)样品中的细胞因子和其他免疫效应分子。Thiskitisidealforuserswhowantaconvenientandsensitiveassay.TheassayisdesignedfortheenumerationofcellssecretinghumanIL-21.ThekitincludesELISpotplatespre-coatedwithmonoclonalantibody,biotinylateddetectionantibody,Streptavidin-ALPandready-to-useBCIP/NBT-plussubstrate.
Pre-coatedplatesreduceassaytimeandminimizevariABIlity.
HumanIL-21ELISpotPLUSkitsarealsoavailablewithStreptavidin-HRPandTMBsubstrate.SeeRelatedproducts.
Speciescross-reactivity
Themonoclonalantibodiesinthiskitcross-reactwithIL-21fromnon-humanprimates.SeetheHuman/NHPcross-reactivitytable.
AnalyteInformation
IL-21
Interleukin-21(IL-21,IL21)isprimarilysecretedbyCD4+Tcells(inparticularfollicularTcellsandTh17)andisanimportantregulatorofimmuneresponses;forTh17cells,IL-21isanautocrineregulatorsustainingTh17development.IL-21alsoregulatesthedevelopmentofotherTcellsaswellasBcells,NKcellsanddendriticcells.AreasofparticularinterestforresearchonIL-21includeautoimmuneandinflammatorydiseases,cancerresearchbutalsobasicstudiesone.g.BcellsandTcells,inparticularTh17cells.
Application: |
|
---|---|
Reactivity: |
|
Contents: |
|
Size: | 10plates |
Otherformats: | ClicktoviewallHuman/NHPIL-21products |
|