Erlotinib HCl is an anti-cancer agent targeting epidermal growth factor receptor (EGFR) tyrosine kinase ATP binding sites, which are commonly overexpressed and sometimes mutated in a variety of cancers.Erlotinib prevents the formation of EGFR homodimers leading to suppression of signal transmittance and tumor growth inhibition.Additionally, erlotinib suppresses cyclin-dependent kinase 2 (Cdk2).It has been shown to be effective against non-small cell lung cancer and pancreatic cancer.

Product SpecificationsErlotinib HClTarceva®

MOLECULAR BIOLOGY GRADE

Formula: C₂₂H₂₃N₃O₄

MW: 393.44 g/mol

Storage/Handling: Store at 2-8 °C. Product is soluble in acid (pH 2) at 0.4 mg/mL.

PubChem Chemical ID: 176870

Air shipments may require special packaging and a small additional box charge.

★活体技术荧光检测荧光蛋白标记适用于标记细胞、病毒、基因等，通常使用的是 GFP、EGFP、RFP（DsRed）等；荧光染料标记适用于标记抗体、多肽、小分子药物等；常用的有 Cy3、Cy5、Cy5.5 及 Cy7量子点标记（新的标记方法）适用于标记肿瘤，主要应用在活细胞实时动态荧光观察与成像；量子点（quantum dot) 是一种能发射荧光的半导体纳米微晶体，外观恰似一极小的点状物。量子点荧光比有机荧光染料的发射光强的 20 倍，稳定性强 100 倍以上，具有荧光发光光谱较窄、量子产率高、不易漂白、激发光谱宽、颜色可调，并且光化学稳定性高，不易分解等诸多优点。