GoldBiogrowthfactorsaremanufacturedforRESEARCHUSEONLYandcannotbesoldforhumanconsumption!
RecombinantHumanParathyroidHormone(PTH)ParathyrinParathormoneParathyroidHormone1(PTH1)
HumanParathyroidHormone(PTH)isahormoneexpressedandsecretedaspreproPTHbychiefcellsoftheparathyroidglandswhenextracellularcalciumlevelsarelow.Itiscoexpressedwithfurin,theenzymebelievedtoberesponsIBLeforprocessingproPTHtoPTH.PTHisaligandfortwodifferentreceptors,PTH1RinboneandkidneyandPTH2RfoundintheCNS,pancreas,andplacenta.PTHplaysamajorroleinbonemetabolismandcalciumhomeostasis,aswellasrenalexcretion.Inosteoblasts,PTHstimulatesglycogenesisandtheuptakeof[1-(14)C]-2-deoxy-D-glucose(2DG).
SterileFilteredWhitelyophilizedpowder.Purifiedandtestedforuseincellculture.
Source:Escherichiacoli
MW:~9.4kDa(84aminoacids)
Purity:>97%bySDS-PAGEandHPLCanalyses
BIOLOGicalActivity:Fullybiologicallyactivewhencomparedtostandard.TheED50asdeterminedbyitsABIlitytoinducecAMPaccumulationinmurineMC3T3E1cellsislessthan50ng/ml,correspondingtoaspecificactivityof>2.0×104IU/mg.
Storage/Handling:Storedesiccatedat-20°C.
HGNC:9606
NOTFORHUMANUSE!
Additionalresourcesforthisproteinmaybefoundat:OMIM
★活体技术荧光检测荧光蛋白标记适用于标记细胞、病毒、基因等，通常使用的是 GFP、EGFP、RFP（DsRed）等；荧光染料标记适用于标记抗体、多肽、小分子药物等；常用的有 Cy3、Cy5、Cy5.5 及 Cy7量子点标记（新的标记方法）适用于标记肿瘤，主要应用在活细胞实时动态荧光观察与成像；量子点（quantum dot) 是一种能发射荧光的半导体纳米微晶体，外观恰似一极小的点状物。量子点荧光比有机荧光染料的发射光强的 20 倍，稳定性强 100 倍以上，具有荧光发光光谱较窄、量子产率高、不易漂白、激发光谱宽、颜色可调，并且光化学稳定性高，不易分解等诸多优点。
