GoldBiogrowthfactorsaremanufacturedforRESEARCHUSEONLYandcannotbesoldforhumanconsumption!
RecombinantHumanInsulin-likeGrowthFactor-1,15NStableIsotopeLabeledSomatomedinC,15NStableIsotopeLabeledTheInsulin-likegrowthfactors(IGFs)aremitogenicpolypeptidegrowthfactors,predominantlyproducedintheliver,thatstimulatetheproliferationandsurvivalofvariouscelltypes,includingmuscle,boneandcartilagetissueinvitro.IGFsbelongtotheInsulingenefamilyandaresimilarbystructureandfunctiontoinsulin,buthaveamuchhighergrowth-promotingactivity.IGF1expressionisregulatedbygrowthhormone,whileIGF2expressionisinfluencedbyplacentalactogen.BothIGF1andIGF2signalthroughthetyrosinekinasetypeIreceptor(IGFIR).MatureIGFsaregeneratedthroughproteolyticprocessingofinactiveprecursorproteins.RecombinanthumanIGF1isaglobularproteincontaining70aminoacidsand3intra-moleculardisulfidebonds.Thisparticularproducthasbeenlabeledwiththestable15Nisotopetohelptrackitsactivity.
SterileFilteredWhitelyophilizedpowder.Purifiedandtestedforuseincellculture.
Source:Escherichiacoli
MW:~7.7kDa(70aminoacids)
Purity:>97%bySDS-PAGEandHPLCanalyses.
Storage/Handling:Storedesiccatedat-20°C.
HGNC:5464
NOTFORHUMANUSE!
Additionalresourcesforthisproteinmaybefoundat:OMIM
★活体技术荧光检测荧光蛋白标记适用于标记细胞、病毒、基因等，通常使用的是 GFP、EGFP、RFP（DsRed）等；荧光染料标记适用于标记抗体、多肽、小分子药物等；常用的有 Cy3、Cy5、Cy5.5 及 Cy7量子点标记（新的标记方法）适用于标记肿瘤，主要应用在活细胞实时动态荧光观察与成像；量子点（quantum dot) 是一种能发射荧光的半导体纳米微晶体，外观恰似一极小的点状物。量子点荧光比有机荧光染料的发射光强的 20 倍，稳定性强 100 倍以上，具有荧光发光光谱较窄、量子产率高、不易漂白、激发光谱宽、颜色可调，并且光化学稳定性高，不易分解等诸多优点。
