Description

Acalabrutinib (ACP-196) is an irreversible inhibitor of Bruton’s tyrosine kinase (BTK), which is responsible for the maturation of B-cells. Its high selectivity to bind the residue Cys481 in the active site of BTK is a sought after feature for oncology research. Studies on mice and human cells demonstrate the high affinity of ACP-196 and its low affinity toward similar proteins in T-cell maturation.

Product SpecificationsAcalabrutinibACP-196

Formula: C₂₆H₂₃N₇O₂

MW: 465.51 g/mol

Storage/Handling: Store desiccated at -20°C.

PubChem Chemical ID: 71226662

>>> 更多资讯详情请访问蚂蚁淘商城