Guanidine HCl is a freely soluble chaotropic agent routinely used for protein denaturation and folding.

In order to study their molecular properties and amino acid composition, proteins must be denatured from their folded state. The exact mechanism of protein unfolding by guanidine HCl is unclear. However it is speculated that the denaturant migrates into the interior of the protein and forms hydrogen bonds with atoms in the protein backbone.

Guanidine HCl is an agent frequently used to study protein properties and amino acid composition.

Product SpecificationsGuanidine HydrochlorideGuanidine HCl

Formula: CH₅N₃ ∙ HCl

MW: 95.53 g/mol

Storage/Handling: Store at room temperature.

PubChem Chemical ID: 5742

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