Cat-Nr.	102-P65
Size	100 µg
Price	235 €
Category	Polyclonal Antibody
Clone Nr.	Rabbit IgG
Species Reactivity	Human
Formulation	lyophilized
Reconstitution	Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Stability and Storage	The lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
Antigen	recombinant human HB-EGF (Cat# 100-185)
Application	WB, ELISA
Synonyms	HBEGF; DTR; DTS; DTSF; HEGFL
Description	HB-EGF is an EGF related growth factor that signals through the EGF receptor, and stimulates the proliferation of smooth muscle cells (SMC), fibroblasts, epithelial cells, and keratinocytes. HB-EGF is expressed in numerous cell types and tissues, including vascular endothelial cells and SMC, macrophages, skeletal muscle, keratinocytes, and certain tumor cells. The ability of HB-EGF to specifically bind heparin and heparin sulfate proteoglycans is distinct from other EGF-like molecules, and may be related to the enhanced mitogenic activity, relative to EGF, that HB-EGF exerts on smooth muscle cells. The human HB-EGF gene encodes a 208 amino acid transmembrane protein, which can be proteolytically cleaved to produce soluble HB-EGF.
Uniprot ID	Q99075
Protein RefSeq	NP_001936.1
mRNA RefSeq	NM_001945

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