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Relia Tech/Rabbit Anti-human IL-2 receptor alpha/100 µg/102-P47

价格
¥4700.00
货号:102-P47
浏览量:127
品牌:Relia Tech
服务
全国联保
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正规发票
签订合同
商品描述
Cat-Nr.102-P47
Size100 µg
Price235 €
CategoryPolyclonal Antibody
Clone Nr.Rabbit IgG
Species ReactivityHuman
Formulationlyophilized from PBS
BufferPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Stability and StorageThe lyophilized antibody is stable for at least 2 years from date of receipt at -20°C. The reconstituted antibody is stable for at least two weeks at 2-8°C. Frozen aliquots are stable for at least 6 months when stored at -20°C.
PreparationProduced from sera of rabbits immunized with highly pure recombinant human sIL-2 Receptor alpha. Anti-Human sIL-2 Receptor alpha-specific antibody was purified by affinity chromatography employing immobilized human sIL-2 Receptor alpha as matrix.
AntigenRecombinant Human sIL-2 Receptor α (CHO cell derived)
ApplicationELISA, WB
Synonymssoluble IL-2 receptor, TAC-antigen, CD25 antigen, IL2RA; CD25; IL2R; TCGFR; IDDM10
DescriptionThe IL-2 receptor system consists of three non-covalently linked subunits termed IL-2R alpha, IL-2R beta, and IL-2R gamma. The IL-2R alpha is a type I transmembrane protein consisting of a 219 amino acid extracellular domain, a 19 amino acid transmembrane domain and a 13 amino acid intracellular domain, which is not involved in the transduction of IL-2 signals. Proteolytic processing of IL-2R alpha releases the entire extracellular domain of IL-2R alpha thereby generating a 219 amino acid soluble protein called soluble IL-2R alpha (sIL-2R alpha). The homodimeric form binds IL-2 (KD=10mM) and facilitates IL-2 signaling. The secreted sIL-2R alpha is expressed on leukemia cells, lymphoma cells, newly activated T and B cells, as well as on approximately 10% of NK cells. Recombinant human sIL-2R alpha is a 24.8 kDa protein containing 219 amino acid residues consisting of only the extracellular domain of IL-2R alpha. Due to glycosylation, IL-2R alpha has an approximate molecular weight of 31 kDa based on SDS-PAGE gel and Mass Spectrometry.
Uniprot IDP01589
Protein RefSeqNP_000408.1
mRNA RefSeqNM_000417.2
Relia Tech类似于我们在大肠杆菌中的蛋白质表达服务,我们还提供了围绕昆虫细胞中基因和蛋白质表达(尤其是信号蛋白质)的模块化服务系统。ReliaTech的“杆状病毒表达服务(BVS)”分为一系列步骤,这些步骤可以单独执行或组合执行,因此您可以选择实际需要的步骤。这些服务旨在充分满足从基因表达到蛋白质纯化的所有特定需求-从通过重组杆状病毒构建,高滴度重组杆状病毒生产,重组蛋白批量生产以及最终蛋白质纯化的基因克隆到杆状病毒转移载体开始。所有步骤均在无血清培养基中进行,以确保安全性并产生高纯度的重组蛋白。除常规项目更新外,您还将在每个服务步骤的最后收到进度报告。我们将根据您的授权逐步指导您继续进行。