Cat-Nr.	101-M765
Size	100 µg
Price	275 €
Category	Monoclonal Antibody
Clone Nr.	(#7W11)
Isotype	IgG1
Species Reactivity	Human
Formulation	lyophilized
Buffer	PBS
Reconstitution	Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and Storage	Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Preparation	This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with human recombinant protein of TfR extracellular domain.
Antigen	Human recombinant TfR EC domain
Application	FC
Synonyms	TFRC; T9; TR; TFR; p90; CD71; TFR1; TRFR
Description	Transferrin receptors are transmembrane, homodimeric proteins that play a role in iron transport, uptake, and storage. TfR is an essential receptor, found on almost all cell types, regulated by intracellular iron concentration, and has a high affiinity for transferrin. Soluble TfR (sTfR) arises from the proteolysis of TfR into monomers that can be measured in plasma and serum. TfR2 has limited tissue distribution (hepatocytes and enterocytes), is regulated by the cell cycle, and binds transferrin poorly.
Uniprot ID	P02786
Protein RefSeq	NP_003225.2
mRNA RefSeq	NM_003234.2

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