VersicanMonoclonalAntibody

ORDERINGINFORMATIONCatalogNo.:56542(cloneS351-23)Size:100uginPBS,pH7.4;50%glycerol,0.09%sodiumazide.PurifiedbyProteinGaffinitychromatography.

BACKGROUND

Versican(chondroitinsulfateproteoglycan

2)isalargeextracellularmatrixproteo-glycaninvolvedincellgrowth

anddifferentiation.Versicancontainshyaluronicacidandglycosaminoglycan-bindingdomains,epidermalgrowthfactor-likerepeats,aLectin-likesequence,andacomplementregulatoryprotein-likedomain.Splicevariantsdiffergreatlyinlengthanddegreeofmodificationbyglycoaminoglycanchains.AccumulationaroundsmoothmusclecellsinatheroscleroticlesionssuggestsaroleforVersicaninatherogenesis.

SPECIFICATIONSUMMARYAntigen:Fusionproteincorrespondingtoaa362-585ofmouseVersican(accessionno.Q62059).HostSpecies:MouseAntibodyClass:IgG1

SPECIFICITY

ThisantibodyrecognizesmouseandratVersican.

APPLICATIONS

Immunoblotting:useat1ug/ml.Predictedmolecularweightis>350kDa.

Positivecontrol:Mousebrainlysate.Thesearerecommendedconcentrations.Usershoulddetermineoptimalconcentrationsfortheirapplication.

DILUTIONINSTRUCTIONS

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

STORAGEANDSTABILITY

Thisantibodyisstableforatleastone(1)yearat-20oC.Avoidrepeatedfreezingandthawing.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

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