productdatasheet

Anti-FBG4(FBox4)Antibody

ORDERINGINFORMATION

CatalogNo.:28105

Size:100ugIgGinPBS,pH7.4,purifiedbyimmunoaffinitychroma-tography.

BACKGROUND

F-boxproteins,criticalcomponentsoftheconservedubiquitin-proteinligasecomplexSCF(Skp1/Cdc53-Cullin1/F-box),recruitsubstratesforubiquitinationandconsequentdegradationthroughtheirspecificprotein-proteininteractiondomains.NovelhumanF-boxproteinsnamedFBG1,FBG2,FBG3,FBG4and

FBG5constituteasubfamilyofmammalianF-boxproteins.FBGgenesareexpressedinalimitednumberofhumantissuesincludingkidney,liver,brainandmuscletissues.

SPECIFICATIONSUMMARY

Immunogen:Syntheticpeptidecorrespondingtoaminoacids70-85(LQLARDRSAEGRALYA)ofhuman

FBG4conjugatedtoKLHattheN-terminus.

HostSpecies:Rabbit

StABIlizers:NonePreservatives:None.Availableonrequest.

SPECIFICITY

ThisantibodyrecognizesaminoacidshumanFBG4.SequencehomologytomouseandratFBG4proteinis100%.

APPLICATIONS

Immunoblotting:useat1:500dilution.Abandofapproximately31kDaisdetected.

Positivecontrol:recombinanthumanfulllengthFBG4protein.

DILUTIONINSTRUCTIONS

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

STORAGEANDSTABILITY

Thisantibodyisstableforatleastone

(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.

BACKGROUNDREFERENCE

Ilyin,GPetal.(2002)Gene296:11-20.

Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.

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