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苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
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0512-67156496
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info@ebiomall.com
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https://www.ebiomall.com
商品描述
Cataloguenumber
ANT-455
Synonyms
Gamma-synuclein,Persyn,Breastcancer-specificgene1protein,Synoretin,SR,SNCG,BCSG1,PERSYN,PRSN,g-Synuclein.
Type
PolyclonalRabbitAntibody.
Introduction
γ-synuclein(Originallyknownasabreastcancerspecificgeneproduct,BCSG1)isanacidicneuronalproteinof127aminoacids.Gamma-SynucleinisamemberoftheSynucleinproteinfamily,whichisbelievedtobeinvolvedinthepathogenesisofneurodegenerativediseases.HighlevelsofGamma-SynucleinhavebeenfoundinadvancedbreastcarcinomassuggestingacorrelationbetweenoverexpressionofSNCGandbreasttumordevelopment.Synuclein-Gammaisfoundmostlyintheperipheralnervoussystem(inprimarysensoryneurons,sympatheticneurons,andmotorneurons)andretina.SNCGisalsoidentifiedinthebrain,ovariantumors,andintheolfactoryepithelium.SNCGexpressioninbreasttumorsisaMarkerfortumorprogression.Amodificationintheexpressionofgamma-synucleinhasbeendetectedintheretinaofAlzheimer""spatients.
Immunogen
Recombinanthumanγ-Synucleinaminoacids1-127purifiedfromE.coli.
PhysicalAppearance
Sterilefilteredcolorlesssolution.
Formulation
1mg/mlcontainingPBS,pH-7.4,&0.1%SodiumAzide.
StorageProcedures
Forperiodsupto1monthstoreat4°C,forlongerperiodsoftime,storeat-20°C.Preventfreezethawcycles.
StABIlity/ShelfLife
12monthsat-20°C.1monthat4°C.
Applications
γ-SynucleinantibodyhasbeentestedbyELISAandWesternblotanalysistoassurespecificityandreactivity.Sinceapplicationvaries,however,eachinvestigationshouldbetitratedbythereagenttoobtainoptimalresults.RecommendeddilutionrangeforWesternblotanalysisis1:500~2,000.Recommendedstartingdilutionis1:1,000.
Usage
Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theproductmaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.