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苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
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info@ebiomall.com
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https://www.ebiomall.com
商品描述
Catalogue number
ANT-162
Synonyms
IPF1, IUF1, IDX-1, MODY4, PDX1, STF-1, Insulin promoter factor 1, Pancreas Duodenum Homeobox-1.
Type
Polyclonal Rabbit Antibody.
Introduction
PDX1 activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. IPF1 is particularly involved in glucose-dependent regulation of insulin gene transcription. Pancreas Duodenum Homeobox-1 binds preferentially the DNA motif 5'-[ct]taat[tg]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, it is required for maintaining the hormone-producing phenotype of the beta-cell.
Immunogen
Recombinant PDX1 E.Coli derived.
Specificity
Human and Mouse PDX-1.
Molecular Weight
35-40 kDa.
Stability
Stable for 2 yeas at -20°C. Avoid freeze/thaw cycles.
Applications
Western Blot: 1:1,000
Immunohistochemistry: 1:500
Optimal working dilutions must be determined by end user.
Routinely evaluated by western blot on lysates of rat pancreatic cell line INS-1
Usage
Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
