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Prospec/HBV core (1-186 a.a.)/Hepatitis B Virus Core (1-186 a.a.) Recombinant/1000µg/HBV-232-1000µg-1000µg

价格
¥20000.00
货号:HBV-232-1000µg-1000µg
浏览量:44
品牌:Prospec
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商品描述

Catalogue number

HBV-232

Introduction

Hepatitis B is one of a few known non-retroviralviruses which employ reverse transcriptionas a part of its replication process. (HIV, a completely unrelated virus, also uses reverse transcription, but it is a retrovirus.) HBV invades the cell by binding to surface receptor and become internalized. The viral core particles then migrate to the hepatocyte nucleus and the partially double-stranded, relaxed circular genomes (RC-DNA) are repaired to form a covalently closed circular DNA (cccDNA), which is the template for viral genomic and sub-genomic RNAs by cellular RNA polymerase II. Of these, the pregenomic RNA(pgRNA is selectively packaged into progeny capsids and is then reverse-transcribed into new RC-DNA. The core can either bud into the endoplasmic reticulum to be enveloped or exported from the cell or recycled back into the genome for conversion to cccDNA.

Description

The E.coli derived recombinant protein contains the HBV core immunodominant region amino acids 1-186, and fused to a His tag at N- terminus.

Purification Method

HBV Core protein was purified by proprietary chromatographic technique.

Purity

HBV Core protein is >90% pure as determined by 10% PAGE (Coomassie staining).

Formulation

25mM Tris-HCl pH-8.0, 1.5mM EDTA, 1.5mM Urea, 50% glycerol and 50Mm NaCl.

Stability

HBV Core protein although stable at 4°C for 1 week, should be stored below -18°C.Please prevent freeze thaw cycles.

Specificity

Immunoreactive with sera HBV-infected individuals.

Safety Data Sheet

SDS

Usage

ProSpec"s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
ProSpec是全球著名细胞因子蛋白及相关抗体生产和研发品牌,专注于蛋白生产研发,独有细菌和哺乳动物表达和蛋白折叠技术。目前可提供细胞因子、生长因子、激素、信号蛋白、病毒抗原等近800种重组蛋白和100多种抗体。 ProSpec is an evolving biotech company providing highly purified proteins worldwide which serve the research community with cytokine-related products for cancer, apoptosis, development, endocrinology, immunology, neuroscience, proteases, and stem cell research. Among our proteins are Interferons, Interleukins, Bone Morphogenic Proteins, Tumor Necrosis factors, Leptins, Stem Cell factors, Prolactins, Chemokines, Antibodies, Peptides, Enzymes, Viral Antigens, various growth factors such as: Platelet Derived, Epidermal, Insulin Like, Nerve, Connective Tissue, Vascular Endothelial, Fibroblast and more..... 产品列表: No. 品牌 货号 名称 规格 1 ProSpec PRO-1574 BCL2 Human 5µg 2 ProSpec CYT-1075 IFNA7 Human, Sf9 2µg 3 ProSpec CHM-328 Rantes Human 5µg 4 ProSpec CHM-330 IP 10 Human 5µg 5 ProSpec CYT-575 MIF Human 5µg 6 ProSpec CYT-538 GH Antagonist Chicken 20µg 7 ProSpec CYT-1043 TNFRSF10A Human 2µg 8 ProSpec PRO-2390 CD2 Human, Sf9 2µg 9 ProSpec PRO-2237 CD47 Human 2µg 10 ProSpec CYT-581 Beta NGF Mouse 5µg 11 ProSpec CYT-973 NRP1 Rat 1µg 12 ProSpec HOR-253 FSH Human 2µg 13 ProSpec HOR-275 Thymosin beta 4 1mg 14 ProSpec DEN-005 Dengue Envelope-1 22kDa 100µg 15 ProSpec HEV-235 HEV Mosaic 100µg