Type: Goat IgG

Applications: IF; WB

E=ELISA; FACS; FC=Flow Cytometry; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; IP=Immunoprecipitation; NAC=Non-adherent Cell Assays; NB=Neutralization of Bioactivity; SE=Sandwich ELISA; TPE=Targeted Protein Expression; WB=Western blotting; ; AC=Adherent Cell Assays; FM=Fluorescent Micsroscopy; ; ; BSC-CM5= Biacore Sensor Chip CM5; BSM=Biosactive Small Molecule or Peptide; CDM=Cell Differentiation Media; ; ; ; ; ; Health and Fitness; ; ; DNA Extraction/Purification; ; In vivo Like Assays

Species Reactivity: H; M; R

B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins; All

Format: Affinity Purified - liquid

Immunogen: Synthetic peptide: Peptide with sequence C-NEEKKSKVHYH, from the internal region of the protein sequence according to NP_004373.2.

Corticotropin Releasing Hormone Receptor 1 (CRHR1 or CRF1) is a member of the corticotropin-releasing factor family of G-protein-coupled receptors that also includes CRF2. It is abundantly expressed in the CNS with major expression in the cortex, cerebellum, hippocampus, amygdala, olfactory bulb and pituitary. In the periphery, the receptors are expressed at low levels in the skin, ovary, testis and adrenal gland.

 It mediates stress and anxiety including stress related colonic motor activity.

Image: CRF1 (dilution: 0.3µg/ml) staining in green a dendrite of a neuronal cell in C57 mouse cortex. Counter-stained with DAPI (in blue). Courtesy of Dr Y. Chen, TZ Baram lab, UC Irvine, CA.

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