Type: Rabbit IgG

Applications: IHC

E=ELISA; FACS; FC=Flow Cytometry; FPLC=Fast Protein Liquid Chromatography; GF=Gravity Flow; HPLC=High Performance Liquid Chromatography; ICC=Immunocytochemistry; IF=Immunofluorescence; IHC=Immunohistochemistry; IP=Immunoprecipitation; NAC=Non-adherent Cell Assays; NB=Neutralization of Bioactivity; SE=Sandwich ELISA; TPE=Targeted Protein Expression; WB=Western blotting; ; AC=Adherent Cell Assays; FM=Fluorescent Micsroscopy; ; ; BSC-CM5= Biacore Sensor Chip CM5; BSM=Biosactive Small Molecule or Peptide; CDM=Cell Differentiation Media; ; ; ; ; ; Health and Fitness; ; ; DNA Extraction/Purification; ; In vivo Like Assays

Species Reactivity: M; R

B=Bovine; Ca=Cat; Ch=Chicken; D=Dog; EQ=Equine; GP=Guinea Pig; H=Human; M=Mouse; P=Porcine; Pr=Primate; R=Rat; Rb=Rabbit; Y=Yeast; Xe=Xenopus; Ze=Zebrafish; ; ; ; NA-Not Applicable; STP=Step-Tactin Proteins; All

Format: Whole serum - lyophilized

Immunogen: Synthetic peptide (human) Neurotensin coupled to bovine thyroglobulin (BTg) with glutaraldehyde.

Neurotensin is a 13-amino acid neuropeptide involved in neurotransmission in the CNS and PNS. In the CNS, it interacts with dopamine. It also plays a tonic stimulatory role on HPA axis activity and an inhibitory effect on vasopressin secretion. Through its diverse expression, Neurotensin modulates analgesia, hypothermia, appetite, fear response, gut motility and locomotor activity

Image: Neurotensin staining of rat amygdala.

By selective targeting or blockade of specific neurotensin receptors, investigators have identified potential drugs for use in the treatment of schizophrenia, alcoholism, chronic pain, or cancer.

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