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4000-520-616 / 18915418616
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商品描述
Type:Protein
SpeciesReactivity:H
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;AllRecombinantHumanCD40Ligand(hCD40L),TRAP,TNFSF5 orCD154isamembraneglycoproteinanddifferentiationantigenexpressedonthesurfaceofT-cells.CD40LigandstimulatesB-cellproliferationandsecretionofallimmunoglobulinisotypesinthepresenceofcytokines.CD40Ligandhasbeenshowntoinducecytokineproductionandtumoricidalactivityinperipheralbloodmonocytes.Italsoco-stimulatesproliferationofactivatedT-cellsandthisisaccompaniedbytheproductionofIFN-gamma,TNF-alpha,andIL-2.
Note:hCD40LisfullyBIOLOGicallyactivewhencomparedtoastandard.TheED50,asdeterminedusingT-47Dcells,is<0.04ug/ml.
