Type:RabbitIgG
Applications:IHC;WB
E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssaysSpeciesReactivity:H;M;R;Rb
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;AllFormat:AffinityPurified-liquid
Immunogen:C-terminalsequenceofhumanOPCML.
Opioid-bindingprotein/celladhesionmolecule-like(OPCM-L)isamemberoftheIgLONsubfamilyintheimmunoglobulinproteinsuperfamily.OPCMLislocalizedintheplasmamembraneandmayhaveanaccessoryroleinopioidreceptorfunction.Thisgenehasanorthologinratandbovine.Theopioidbinding-celladhesionmoleculeencodedbytheratgenebindsopioidalkaloidsinthepresenceofacidiclipids,exhibitsselectivityformuligandsandactsasaGPI-anchoredprotein.Sincetheencodedproteinishighlyconservedinspeciesduringevolution,itmayhaveafundamentalroleinmammaliansystems
Images:Top:OPCM-Limmunohistochemicalstainingofparaffin-embeddedhumanstomachcancertissue. Bottom:WesternBlotdetectionofendogenousOPCMLproteinsfromvariousnormalprimarycelllysatesusingOPCMLantibody.ThepredictmolecularweightofOPCMLis34kDa.Duetopost-translationalmodifications,theactualmolecularweightofmatureOPCMLintheSDS-PAGEgelis51kDa.HUVEC:HumanUmbilicalVeinEndothelialCells;ROb:RatOsteoblasts.
