Type:Protein
SpeciesReactivity:H
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;AllNeuron-specificenolasealsocalledNSEisaglycolyticisoenzymewhichissituatedincentralandperipheralneuronsandneuroendocrinecells.Enolase-2isreleasedintotheCSFwhenneuraltissueisinjured.NeoplasmsderivedfromneuralorneuroendocrinetissuereleaseEnolase-2intotheblood.Enolase-2isausefulsubstancethathasbeendetectedinpatientswithcertaintumors,suchasneuroblastoma,smallcelllungcancer,medullarythyroidcancer,carcinoidtumors,pancreaticendocrinetumors,andmelanoma.ENO2is1ofthe3enolaseisoenzymesfoundinmammals.ENO2isoenzyme,isfoundinmatureneuronsandcellsofneuronalorigin.Anexchangefromalphaenolasetogammaenolaseoccursinneuraltissueduringdevelopmentinratsandprimates.
ENO2HumanRecombinantexpressedinE.colicontains434aminoacidsanditsMwis47kDa.TheEnolase-2ispurifiedbyproprietarychromatographictechniques.
