Type:Protein
SpeciesReactivity:H
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;AllTGFBIisanextracellularmatrixproteininducedbytransforminggrowthfactor(TGF)-beta1.TGFBIproteinisinvolvedincellgrowth,celldifferentiation,woundhealingandcelladhesion.Inaddition,somemissensemutationsofTGFBIwereidentifiedinfamiliesaffectedwithhumanautosomaldominantcornealdystrophies.TGFBIgeneencodesfora683amino-acidproteincontaininganRGDmotifandfourinternalrepeateddomainswhichhavehighlyconservedsequencesfoundedinseveralspecies(Fasciclindomain).