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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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商品描述
Type:GoatIgG
Applications:E;IHC;WB
E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssaysSpeciesReactivity:H;M;R
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;AllFormat:AffinityPurified-liquid
Immunogen:Purified,NS0-derived,recombinanthumanLINGO-1(rhLINGO-1;aa40-556;Accession#AAH11057).
LINGO-1(Leucine-richrepeat-andIgdomain-containingnogoreceptor-interactingprotein1)isatransmembraneproteinoftheleucine-richrepeat(LRR)family,ribonucleaseinhibitorsubfamily.ThefourknownLINGOproteinscontainLRRandIgCAMdomainsintheextracellularportionandshare44-61%aaidentity.LINGO-1isrestrictedtothenervoussystemandisconcentratedinthebrainasacomponentoftheNgR1/p75andNgR1/Taj(Troy)signalingcomplexes.LINGO-1negativelyregulatesneuriteoutgrowthandmyelination,andishighlyconserved,showing99%aaidentitybetweenhuman,mouseandrat.
