Product ID B8275Cas No. 107-92-6Purity ≥98%

• Description
• Product Info
• Shipping and Storage
• Downloads
• References

Description

Butyric acid is a fatty acid found in many dairy products that exhibits anticancer activity. Butyric acid inhibits histone deacetylases (HDACs) and induces apoptosis and G1 phase cell cycle arrest in glioma cells. Additionally, butyric acid stimulates epithelial cell proliferation at low doses and inhibits proliferation at high doses.

Product Info

Cas No.PurityFormulaFormula Wt.IUPAC NameSynonymMelting PointSolubilityAppearance

107-92-6

≥98%

C4H8O2

88.10

butanoic acid

Butanoic acid; Butyric acid; Ethylacetic acid

-7°C

Miscible with water, alcohol or ether.

Colorless liquid

Shipping and Storage

Store TempShip Temp

Ambient

Ambient

Downloads

MSDSInfo Sheet

B8275 MSDS PDF

B8275 Info Sheet PDF

References

Kim SW, Hooker JM, Otto N, et al. Whole-body pharmacokinetics of HDAC inhibitor drugs, butyric acid, valproic acid and 4-phenylbutyric acid measured with carbon-11 labeled analogs by PET. Nucl Med Biol. 2013 Oct;40(7):912-8. PMID: 23906667.

Inagaki A, Sakata T. Dose-dependent stimulatory and inhibitory effects of luminal and serosal n-butyric acid on epithelial cell proliferation of pig distal colonic mucosa. J Nutr Sci Vitaminol (Tokyo). 2005 Jun;51(3):156-60. PMID: 16161765.

Komata T, Kanzawa T, Nashimoto T, et al. Histone deacetylase inhibitors, N-butyric acid and trichostatin A, induce caspase-8- but not caspase-9-dependent apoptosis in human malignant glioma cells. Int J Oncol. 2005 May;26(5):1345-52. PMID: 15809727.

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