Hannedoucheetal.(2011)OxysterolsdirectimmunecellmigrationviaEBI2.Nature475:524–527.[Abstract]
MATERIALSAFETYDATASHEET
TRADENAME:7-alpha,25-dihydroxycholesterol
DATEOFISSUE:Oct24,2013
SKU#:2300070012(1mg),2300070052(5mg),2300070102(10mg),2300020013(1g),2300020023(2g),2300020033(3g)
SECTIONI:PRODUCTANDMANUFACTURERINFORMATION
TRADENAME:7α,25-dihydroxycholesterol
Supplier:EtonBioscienceInc.,5820OberlinDrive,Suite108,SanDiego,CA92121 InformationTelephone:800.758.1630
EmergencyTelephone:800.758.1630
SECTIONII:COMPOSITION/INFORMATIONONINGREDIENTS
ChemicalName;7α,25-dihydroxycholesterol
Synonyms:7α,25-dihydroxycholesterol
Hazardousingredients:
MolecularWeight:418.652g/mol
CASNumber:64907-22-8
SECTIONIII:HAZARDIDENTIFICATION
EmergencyOverview
OSHAHazards
NoknownOSHAhazards
HMISClassification
HealthHazard:0
Flammability:0
Physicalhazards:0
NFPARating
HealthHazard:0
Fire:0
ReactivityHazard:0
PotentialHealthEffects
InhalationMaybeharmfulifinhaled.Maycauserespiratorytractirritation.
SkinMaybeharmfulifabsorbedthroughskin.Maycauseskinirritation.
EyesMaycauseeyeirritation.
IngestionMaybeharmfulifswallowed
SECTIONIV:FIRSTAIDMEASURES
Incaseofeyecontact:Checkforandremoveanycontactlenses.Flusheyeimmediatelywithrunningwaterforatleast15minutes.Callaphysician.
Incaseofskincontact:washwithplentyofwater.Gentlyandthoroughlywashthecontaminatedskinwithrunningwater.
Incaseofinhalation:Removetofreshair.Ifnotbreathinggiveartificialrespiration
Incaseofingestion:Nevergiveanythingbymouthtoanunconsciousperson.Rinsemouthwithwater.
SECTIONV:FIREFIGHTINGMEASURES
Flammableproperties:Flashpointnodataavailable.Ignitiontemperaturenodataavailable
Suitableextinguishingmedia:Usewaterspray,alcohol-resistantfoam,drychemicalorcarbondioxide.
Specialprotectiveequipmentforfire-fighters:Wearselfcontainedbreathingapparatusforfirefightingifnecessary.
SECTIONVI:ACCIDENTALRELEASEMEASURES
Personalprecautions:Avoiddustformation.
Environmentalprecaution:Donotletproductenterdrains.
Methodsforcleaningup:Sweepupandshovel.Keepinsuitable,closedcontainersfordisposal.
SECTIONVII:HANDLINGANDSTORAGE
Handling:Provideappropriateexhaustventilationatplaceswheredustisformed.Normalmeasuresforpreventivefireprotection.
Storage:Keepcontainertightlyclosedinadryandwell-ventilatedplace.Recommendedstoragetemperature:-20°C
SECTIONVIII:EXPOSURECONTROLS/PERSONALPROTECTION
Containsnosubstanceswithoccupationalexposurelimitvalues.
SECTIONIX:PHYSICALANDCHEMICALPROPERTIES
Appearance:Formpowder,lyophilized
Molecularformula:C27H46O3
MolecularWeight:418.652g/mol
pH:nodataavailable
Meltingpoint:nodataavailable
Boilingpoint:nodataavailable
Flashpoint:nodataavailable
Ignitiontemperature:nodataavailable
Lowerexplosionlimit:nodataavailable
Upperexplosionlimit;nodataavailable
Watersolubility:nodataavailable
SECTIONX:STABILITYANDREACTIVITY
Storagestability:Stableunderrecommendedstorageconditions.
Materialstoavoid:Strongoxidizingagents
Hazardousdecompositionproducts:Hazardousdecompositionproductsformedunderfireconditions.-Carbonoxides
SECTIONXI:TOXICOLOGICALINFORMATION
Acutetoxicity:nodataavailable
Irritationandcorrosion:nodataavailable
Sensitisation:nodataavailable
Chronicexposure
IARC:Nocomponentofthisproductpresentatlevelsgreaterthanorequalto0.1%isidentifiedasprobable,possIBLeorconfirmedhumancarcinogenbyIARC.
ACGIH:Nocomponentofthisproductpresentatlevelsgreaterthanorequalto0.1%isidentifiedas
acarcinogenorpotentialcarcinogenbyACGIH.
NTP:Nocomponentofthisproductpresentatlevelsgreaterthanorequalto0.1%isidentifiedas
aknownoranticipatedcarcinogenbyNTP.
OSHA:Nocomponentofthisproductpresentatlevelsgreaterthanorequalto0.1%isidentifiedas
acarcinogenorpotentialcarcinogenbyOSHA.
PotentialHealthEffects
Inhalation:Maybeharmfulifinhaled.Maycauserespiratorytractirritation.
Skin:Maybeharmfulifabsorbedthroughskin.Maycauseskinirritation.
Eyes:Maycauseeyeirritation.
Ingestion:Maybeharmfulifswallowed.
SECTIONXII:ECOLOGICALINFORMATION
Eliminationinformation(persistenceanddegradability):nodataavailable
Ecotoxicityeffects:nodataavailable
Furtherinformationonecology:nodataavailable
SECTIONXIII:DISPOSALCONSIDERATIONS
Product:Observeallfederal,state,andlocalenvironmentalregulations.
Contaminatedpackaging:Disposeofasunusedproduct.
SECTIONXIV:TRANSPORTINFORMATION
DOT:NotDangerousgoods
IMDG:NotDangerousgoods
IATAclass:NotDangerousgoods
SECTIONXV:REGULATORYINFORMATION
OSHAHazards:NoknownOSHAhazards
TSCAStatus:NotOnTSCAInventory.CasNumber:64907-22-8
DSLStatus:ThisproductcontainsthefollowingcomponentsthatarenotontheCanADIanDSLnorNDSLlists.CasNumber:64907-22-8
SARA302Components:NochemicalsinthismaterialaresubjecttothereportingrequirementsofSARATitleIII,Section302.
SARA313Components:ThismaterialdoesnotcontainanychemicalcomponentswithknownCASnumbersthatexceedthethreshold(DeMinimis)reportinglevels
establishedbySARATitleIII,Section313.
SARA311/312Hazards:NoSARAHazards
MassachusettsRightToKnowComponents:NoComponentsListed
PennsylvaniaRightToKnowComponents:7α,25-dihydroxycholesterolCasNumber:64907-22-8
NewJerseyRightToKnowComponents:7α,25-dihydroxycholesterolCasNumber:64907-22-8
CaliforniaProp.65Components:ThisproductdoesnotcontainanychemicalsknowntoStateofCaliforniatocausecancer,birth,oranyotherreproductivedefects.
SECTIONXVI:OTHERINFORMATION
Theinformationaboveisbelievedtobeaccurateandrepresentsthebestinformationcurrentlyavailabletous.However,wemakenowarrantyofmerchantabilityoranyotherwarranty,expressorimplied,withrespecttosuchinformation.Usersshouldmaketheirowninvestigationstodeterminethesuitabilityoftheinformationfortheirparticularpurposes.EtonBioscienceInc.shallnotbeheldliableforanydamagesorotherconsequencesresultingfromhandlingorfromcontactwiththeaboveproduct.
ENDOFDATASHEET
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