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Product Description

Aldehyde-PEG-Aldehyde (ALD-PEG-ALD) is a linear bifunctional crosslinking PEG reagent with one aldehyde聽at both ends of PEG. 聽聽Aldehyde reacts with amine and N-terminal of peptide and protein to form an imine containing a C=N double bond, which can be further reduced to a more stable C-N bond.聽聽PEG aldehyde or ketone derivatives can be used in reversible PEGylation through its reaction with hydrazine or hydrazide forming a hydrolytic acyl hydrazone linkage.

Additional information

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