Product ID C1869Cas No. 17397-89-6Purity ≥98%

• Description
• Product Info
• Shipping and Storage
• Downloads
• References

Description

Cerulenin is an inhibitor of fatty acid synthase found in Cephalosporium. Cerulenin exhibits antibiotic, antifungal, and anticancer chemotherapeutic activities. In cellular and animal models of colon cancer, cerulenin induces apoptosis and cellular death and decreases tumor growth. Cerulenin may also inhibit insulin secretion.

Product Info

Cas No.PurityFormulaFormula Wt.Chemical NameIUPAC NameSynonymMelting PointSolubilityAppearance

17397-89-6

≥98%

C12H17NO3

223.27

(2R,3S)-3-[(4E,7E)-1-Oxo-4,7-nonadienyl]oxirane- carboxamide

(2R,3S)-3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboxamide

Helicocerin

93-94°C

Soluble in ethanol, acetone, or benzene. Slightly soluble in water.

White powder

Shipping and Storage

Store TempShip Temp

-20°C

Ambient

Downloads

MSDSInfo Sheet

C1869 MSDS PDF

C1869 Info Sheet PDF

References

Straub SG, Sharp GW. Inhibition of insulin secretion by cerulenin might be due to impaired glucose metabolism. Diabetes Metab Res Rev. 2007 Feb;23(2):146-51. PMID: 16705622.

Price AC, Choi KH, Heath RJ, et al. Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism. J Biol Chem. 2001 Mar 2;276(9):6551-9. PMID: 11050088.

Huang P, Zhu S, Lu S, et al. Cerulenin inhibits growth of human colonic carcinoma in nude mice. Zhonghua Bing Li Xue Za Zhi. 2000 Dec;29(6):435-8. PMID: 11866947.

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