Product ID I1257Cas No. 54-42-2Purity ≥98%

• Description
• Product Info
• Shipping and Storage
• Downloads
• References

Description

Idoxuridine is an antiviral clinically used to treat herpes simplex keratitis and other ocular herpes infections. Idoxuridine is a nucleoside analog of deoxyuridine that is incorporated into DNA, inhibiting chain elongation. Idoxuridine also shows benefit as a radiation/chemotherapy sensitizer in glioma cells.

Product Info

Cas No.PurityFormulaFormula Wt.Chemical NameIUPAC NameSynonymMelting PointSolubilityAppearance

54-42-2

≥98%

C9H11IN2O5

354.10

2-Deoxy-5-iodouridine

1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione

IdU IdUR; IUdR; IdUrd; Dendrid; (+)-5-Iodo-2-deoxyuridine

164-166°C

Slightly soluble in water (2 mg/ml) or acetone (1.6 mg/ml).

White to off white powder

Shipping and Storage

Store TempShip Temp

-20°C

Ambient

Downloads

Info Sheet

I1257 Info Sheet PDF

References

Wilhelmus KR. Antiviral treatment and other therapeutic interventions for herpes simplex virus epithelial keratitis. Cochrane Database Syst Rev. 2010 Dec 8;(12):CD002898. PMID: 21154352.

Schultz CJ, Gaffney DK, Lindstrom MJ, et al. Iododeoxyuridine radiosensitization of human glioblastoma cells exposed to acute and chronic gamma irradiation: mechanistic implications and clinical relevance. Cancer J Sci Am. 1995 Jul-Aug;1(2):151-61. Erratum in: Cancer J Sci Am. 1996 Jan-Feb;2(1):15. PMID: 9166468.

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