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Biosensis/Mouse monoclonal to human protein kinase minibrain homolog [7D10]: IgG/M-829-100/100 µg

价格
¥6540.00
货号:M-829-100
浏览量:120
品牌:Biosensis
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商品描述
Description
Proteinkinaseminibrainhomologphosphorylatesserine,threonineandtyrosineresiduesinitssequenceaswellasinexogenoussubstrates.Itmayplayasignificantroleinasignalingpathwayregulatingcellproliferationandmaybeinvolvedinbraindevelopment.Thereare5namedisoformsproducedbyalternativesplicing.Itisexpressedubiquitouslywithhighestlevelsinskeletalmuscle,testis,fetallungandkidney,andinthedevelopingcentralnervoussystem.Itlocalisestothenucleusspeckle.Thisproteinisoverexpressed1.5-foldinfetalDownsyndromebrainandconsideredastrongcandidateforlearningdefectsassociatedwithDownsyndrome.Itbelongstotheproteinkinasesuperfamily,CMGCser/ThrproteinkinasefamilyandMNB/DYRKsubfamilly.
BatchNo.Seeproductlabel
Unitsize100µg
AntigenPartialrecombinantproteinofhumanproteinkinaseminibrainhomolog(aa674to763)withaGSTtag.
Clone7D10
OtherNamesDualspecificitytyrosine-phosphorylation-regulatedkinase1A;MNBH;HP86;DualspecificityYAK1-relatedkinase;hMNB;DYRK1A
AccessionDYR1A_HUMAN
ProducedinMouse
PurityProteinGpurifiedimmunoglobulin
ApplicationsDirectandsandwichELISAandWBarerecommendedforthisantibody.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificitySpecificityhasbeenconfirmedbyWBanddirectELISAagainsttheantigen.
Cross-reactivityThisantibodycrossreactswithmouseandratproteinkinaseminibrainhomologproteins.
BlastitToseethesharedidentitybetweendifferentspeciesorotherproteins,followthelinkintheAccessionfield,selectthesequencethatyouareinterestedinandcopyandpasteitHEREandblast/formatit.
FormLyophilisedfromPBSpH7.2
ReconstitutionReconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial.
StorageAfterreconstitutionkeepaliquotsat-20°CforhigherstABIlityorat4°Cwithanappropriateantibacterialagent.Glycerol(1:1)maybeaddedforadditionalstability.Avoidrepetitivefreeze/thawcycles.
ExpiryDate12monthswhenstoredat-20°C