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蚂蚁淘在线 / 品牌中心 / Biosensis / Biosensis/Mouse monoclonal to human protein kinase minibrain homolog [7D10]: IgG/M-829-100/100 µg
商品描述
Description | Proteinkinaseminibrainhomologphosphorylatesserine,threonineandtyrosineresiduesinitssequenceaswellasinexogenoussubstrates.Itmayplayasignificantroleinasignalingpathwayregulatingcellproliferationandmaybeinvolvedinbraindevelopment.Thereare5namedisoformsproducedbyalternativesplicing.Itisexpressedubiquitouslywithhighestlevelsinskeletalmuscle,testis,fetallungandkidney,andinthedevelopingcentralnervoussystem.Itlocalisestothenucleusspeckle.Thisproteinisoverexpressed1.5-foldinfetalDownsyndromebrainandconsideredastrongcandidateforlearningdefectsassociatedwithDownsyndrome.Itbelongstotheproteinkinasesuperfamily,CMGCser/ThrproteinkinasefamilyandMNB/DYRKsubfamilly. |
BatchNo. | Seeproductlabel |
Unitsize | 100µg |
Antigen | Partialrecombinantproteinofhumanproteinkinaseminibrainhomolog(aa674to763)withaGSTtag. |
Clone | 7D10 |
OtherNames | Dualspecificitytyrosine-phosphorylation-regulatedkinase1A;MNBH;HP86;DualspecificityYAK1-relatedkinase;hMNB;DYRK1A |
Accession | DYR1A_HUMAN |
Producedin | Mouse |
Purity | ProteinGpurifiedimmunoglobulin |
Applications | DirectandsandwichELISAandWBarerecommendedforthisantibody.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
Specificity | SpecificityhasbeenconfirmedbyWBanddirectELISAagainsttheantigen. |
Cross-reactivity | Thisantibodycrossreactswithmouseandratproteinkinaseminibrainhomologproteins. |
Blastit | Toseethesharedidentitybetweendifferentspeciesorotherproteins,followthelinkintheAccessionfield,selectthesequencethatyouareinterestedinandcopyandpasteitHEREandblast/formatit. |
Form | LyophilisedfromPBSpH7.2 |
Reconstitution | Reconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial. |
Storage | Afterreconstitutionkeepaliquotsat-20°CforhigherstABIlityorat4°Cwithanappropriateantibacterialagent.Glycerol(1:1)maybeaddedforadditionalstability.Avoidrepetitivefreeze/thawcycles. |
ExpiryDate | 12monthswhenstoredat-20°C |