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蚂蚁淘在线 / 品牌中心 / Biosensis / Biosensis/Rabbit polyclonal antibody to human KCNN4 (11-28): Affinity purified/R-1068-100/100 µg
商品描述
| Description |  KCNN4isamulti-passmembraneproteinandbelongstothepotassiumchannelKCNNfamily.KCNN4formsavoltage-independentpotassiumchannelthatisactivatedbyintracellularcalcium.ThechannelisblockedbyclotrimazoleandcharyBDotoxin. |
| BatchNo. | Seeproductlabel |
| Unitsize | 100µg |
| Antigen | Asyntheticpeptidecorrespondingtoaregion(11-28)fromhumanKCNN4.Toenhancetheimmunologicalresponse,thispeptidewascoupledtocarrierproteinBSA. |
| OtherNames | SK4;KCa4;IKCa1;IK1;PutativeGardoschannel;KCNN4;IK1;IKCA1;KCA4;SK4;KCA3.1;Intermediateconductancecalcium-activatedpotassiumchannelprotein4; |
| Accession | O15554KCNN4_HUMAN; |
| Producedin | Rabbit |
| Purity | Affinitypurifiedonantigencolumn |
| Applications | WesternBlotting(WB).Aconcentrationof0.1-0.5µg/mlisrecommendedforWB.HumanKCNN4hasapredictedlengthof427residuesandMWof48kDa.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
| Specificity | ThespecificityofthisantibodyhasbeenconfirmedbyWBagainsttheantigen. |
| Cross-reactivity | Human;rat;predictedtoreactwithmouseduetosequencehomology; |
| Blastit | Ifyouwishtousethisproductinaspeciesotherthanthosespecifiedhereandwanttodeterminetheaminoacidsequencehomologybetweentheimmunogenandthecorrespondingproteininthatspecies,simplycopytheaminoacidsequenceforthisimmunogenandtestitontheBLASTdatabasethatyoucanaccessthroughthelinkbelow.Pleasenotethatantibodiesraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptide.Whatthismeansinpractiseisthatasingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.TheBLASTdatabasecanalsobeusedtocompareanyaminoacidsequencebetweenspeciesandbetweenprotein.ThefullaminoacidsequenceofthetargetproteincanbefoundbyfollowingthelinkintheAccessionfield.YoucanthensearchanyaminoacidsequenceinthetargetproteinusingtheBLASTdatabase.Whenselectingasequencetosearch,pleasechoosecarefully,asthesequenceyouchoosemaybeaprecursorratherthanthematureproteinforexample. |
| Form | Lyophilisedwith5mgBSA,0.9mgNaCl,0.2mgNa2HPO4,0.05mgThimerosal,0.05mgNaN3 |
| Reconstitution | Reconstitutein100µlofsteriledistilledwatertoachieveanantibodyconcentrationof1mg/ml.Centrifugetoremoveanyinsolublematerial. |
| Storage | Atleast12monthsafterpurchaseat2-4°C(lyophilizedformulations).Afterreconstitution,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles |
| ExpiryDate | 12monthsafterpurchase |
| SpecificReferences | 1.RuggieriPetal(2012)TheinhibitionofKCa3.1channelsactivityreducescellmotilityinglioblastomaderivedcancerstemcells.PLoSOne.2012;7(10):e47825. |
