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Biolegend/Purified anti-APP Antibody anti-APP - LN27/25 µl/800904

价格
¥1900.00
货号:800904
浏览量:66
品牌:Biolegend
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Description

Amyloid beta (Aβ or Amyloid beta) denotes peptides of 36-43 amino acids in length that are crucially involved in Alzheimer's disease as the main component of the amyloid plaques found in the brains of Alzheimer patients. The peptides result from the amyloid precursor protein (APP), which is cut by certain enzymes to yield Aβ. Aβ molecules can aggregate to form oligomers (known as "seeds") which are believed to be able to induce other Aβ molecules to also take the misfolded oligomeric form, leading to a chain reaction akin to a prion infection. The seeds or the resulting amyloid plaques are toxic to nerve cells. The other protein implicated in Alzheimer's disease, tau protein, also forms such prion-like misfolded oligomers, and there is some evidence that misfolded Aβ can induce tau to misfold.

Product Details  Biolegend揭示出对神经系统以及影响神经系统的疾病的更好理解的研究可以转化为改善数百万生命的治疗方法。BioLegend提供广泛的产品组合,为您的神经科学实验提供解决方案,包括抗体,免疫测定溶液,重组蛋白,磁性细胞分离和单细胞蛋白质组学试剂。我们的试剂是与该领域的杰出领导者(如迈克尔·J·福克斯基金会)合作建造的(请参见下面的“产品亮点”标签),这表明我们承诺与您的团队合作寻找新发现,为我们的客户带来新的选择和全面的解决方案研究神经系统疾病的解决方案。