品牌分类
- 激酶类
- Eznyme Toolbox: Turbo3C
- 酶工具箱
- Eznyme Toolbox: TurboNuclease
- Eznyme工具箱:涡轮结扎工具箱
- 产品:Eznyme工具箱:Turbo3C
- Kinases: PAK2KD
- Kinases: PAK1KD
- 产品:激酶:PAK1KD
- Kinases: PAK4KD
- Products: Eznyme Toolbox: TurboNuclease
- Eznyme Toolbox: TurboBiotinylation DT Kit
- Eznyme工具箱:涡轮生物素化试剂盒
- Eznyme Toolbox: TurboTEV
- 激酶:PAK6KD
- Kinases: PAK3KD
- Kinases: PAK7KD
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联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
Description: HumanPAK3kinase(UniProt:O75914;NCBI:NM_001128166)belongstoafamilyofp21-activatedkinases.Theseserine/threoninekinasesserveastargetsforthesmallGTPbindingproteinsCdc42andRacandhavebeenimplicatedinawiderangeofBIOLOGicalactivities.OverexpressionofPAK3hasbeendetectedincertaintypesofcancer.MutationsofPAK3havebeenassociatedwithlearningdisABIlityandX-linkedmentalretardation.PAK3KDisarecombinantwildtypehumanPAK3kinasedomain(aminoacids246-544offull-lengthhumanPAK3)expressedinE.coliandpurifiedtonearhomogeneity. MolecularMassandPhosphorylation: Thecalculatedmassis33,758.PAK3KDisphosphorylatedonT421andpartiallyphosphorylatedatadditionalsiteswithmassmeasuredat33,835(1P),33,915(2P),33,995(3P). StabilityandStorage: Stableat-70oCfor12monthsfromdateofreceipt.Proteinshouldbethawedonice.Proteincanbeflash-frozeninliquidnitrogenandstoredat-70oC. Applications: Enzymaticstudies,inhibitorscreen,andselectivityprofiling Highconcentrationavailableforcrystallization |